Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO)
The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, diffic...
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creator | Mylonakis, Eleftherios Lutaakome, Joseph Jain, Mamta K. Rogers, Angela J. Moltó, José Benet, Susana Mourad, Ahmad Files, D. Clark Mugerwa, Henry Kityo, Cissy Kiweewa, Francis Nalubega, Mary Grace Kitonsa, Jonathan Nabenkema, Evelyn Murray, Daniel D. Braun, Dominique Kamel, Dena Higgs, Elizabeth S. Hatlen, Timothy J. Kan, Virginia L. Sanchez, Adriana Tierney, John Denner, Eileen Wentworth, Deborah Babiker, Abdel G. Davey, Victoria J. Gelijns, Annetine C. Matthews, Gail V. Thompson, B. Taylor Lane, H. Clifford Neaton, James D. Lundgren, Jens D. |
description | The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus.
The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus. |
doi_str_mv | 10.1016/j.medj.2022.07.003 |
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The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus.</description><identifier>ISSN: 2666-6340</identifier><identifier>ISSN: 2666-6359</identifier><identifier>EISSN: 2666-6340</identifier><identifier>DOI: 10.1016/j.medj.2022.07.003</identifier><identifier>PMID: 35963234</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>COVID-19 - prevention & control ; COVID-19 - therapy ; COVID-19 Vaccines ; Humans ; Inpatients ; Randomized Controlled Trials as Topic ; Vaccination - methods</subject><ispartof>Med (New York, N.Y. : Online), 2022-08, Vol.3 (8), p.531-537</ispartof><rights>2022 Elsevier Inc.</rights><rights>Copyright © 2022 Elsevier Inc. All rights reserved.</rights><rights>2022 Elsevier Inc. 2022 Elsevier Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-8ff3cc54c22a85b67025c6578dafceea52f7cbbd39d18c05dad2896f55d71d6c3</citedby><cites>FETCH-LOGICAL-c483t-8ff3cc54c22a85b67025c6578dafceea52f7cbbd39d18c05dad2896f55d71d6c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,776,780,881,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35963234$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mylonakis, Eleftherios</creatorcontrib><creatorcontrib>Lutaakome, Joseph</creatorcontrib><creatorcontrib>Jain, Mamta K.</creatorcontrib><creatorcontrib>Rogers, Angela J.</creatorcontrib><creatorcontrib>Moltó, José</creatorcontrib><creatorcontrib>Benet, Susana</creatorcontrib><creatorcontrib>Mourad, Ahmad</creatorcontrib><creatorcontrib>Files, D. Clark</creatorcontrib><creatorcontrib>Mugerwa, Henry</creatorcontrib><creatorcontrib>Kityo, Cissy</creatorcontrib><creatorcontrib>Kiweewa, Francis</creatorcontrib><creatorcontrib>Nalubega, Mary Grace</creatorcontrib><creatorcontrib>Kitonsa, Jonathan</creatorcontrib><creatorcontrib>Nabenkema, Evelyn</creatorcontrib><creatorcontrib>Murray, Daniel D.</creatorcontrib><creatorcontrib>Braun, Dominique</creatorcontrib><creatorcontrib>Kamel, Dena</creatorcontrib><creatorcontrib>Higgs, Elizabeth S.</creatorcontrib><creatorcontrib>Hatlen, Timothy J.</creatorcontrib><creatorcontrib>Kan, Virginia L.</creatorcontrib><creatorcontrib>Sanchez, Adriana</creatorcontrib><creatorcontrib>Tierney, John</creatorcontrib><creatorcontrib>Denner, Eileen</creatorcontrib><creatorcontrib>Wentworth, Deborah</creatorcontrib><creatorcontrib>Babiker, Abdel G.</creatorcontrib><creatorcontrib>Davey, Victoria J.</creatorcontrib><creatorcontrib>Gelijns, Annetine C.</creatorcontrib><creatorcontrib>Matthews, Gail V.</creatorcontrib><creatorcontrib>Thompson, B. Taylor</creatorcontrib><creatorcontrib>Lane, H. Clifford</creatorcontrib><creatorcontrib>Neaton, James D.</creatorcontrib><creatorcontrib>Lundgren, Jens D.</creatorcontrib><title>Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO)</title><title>Med (New York, N.Y. : Online)</title><addtitle>Med</addtitle><description>The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus.
The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus.</description><subject>COVID-19 - prevention & control</subject><subject>COVID-19 - therapy</subject><subject>COVID-19 Vaccines</subject><subject>Humans</subject><subject>Inpatients</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Vaccination - methods</subject><issn>2666-6340</issn><issn>2666-6359</issn><issn>2666-6340</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UU1rGzEUFKWlCUn-QA5Fx_SwW32stLtQCsH9Mhh8SXMVsvTWkVlLrqTd0n9fGSchveTyJPTmzRvNIHRNSU0JlZ929R7srmaEsZq0NSH8DTpnUspK8oa8fXE_Q1cp7QghTFBOe_YenXHRS854c46mFaQUfMJDDHusPXY-Q_Q6u-D1iHN0pcKsx6k8-S2etTHu1MYpR51h66BMh4gjmDBDBFs4DgUBPif8x-UHvFjfL79WtMc397d3y8X64yV6N-gxwdXjeYF-ff92t_hZrdY_lovbVWWajueqGwZujGgMY7oTG9mWLxgp2s7qwQBowYbWbDaW95Z2hgirLet6OQhhW2ql4Rfoy4n3MG2KXaZIinpUh-j2Ov5VQTv1f8e7B7UNs-p5y6lsCsHNI0EMvydIWe1dMjCO2kOYkmJFEu2OpUDZCWpiSCnC8LyGEnWMTO3UMTJ1jEyRVpXIytCHlwKfR54CKoDPJwAUm2YHUSVTnDVgXfE7Kxvca_z_AKIbqk4</recordid><startdate>20220812</startdate><enddate>20220812</enddate><creator>Mylonakis, Eleftherios</creator><creator>Lutaakome, Joseph</creator><creator>Jain, Mamta K.</creator><creator>Rogers, Angela J.</creator><creator>Moltó, José</creator><creator>Benet, Susana</creator><creator>Mourad, Ahmad</creator><creator>Files, D. Clark</creator><creator>Mugerwa, Henry</creator><creator>Kityo, Cissy</creator><creator>Kiweewa, Francis</creator><creator>Nalubega, Mary Grace</creator><creator>Kitonsa, Jonathan</creator><creator>Nabenkema, Evelyn</creator><creator>Murray, Daniel D.</creator><creator>Braun, Dominique</creator><creator>Kamel, Dena</creator><creator>Higgs, Elizabeth S.</creator><creator>Hatlen, Timothy J.</creator><creator>Kan, Virginia L.</creator><creator>Sanchez, Adriana</creator><creator>Tierney, John</creator><creator>Denner, Eileen</creator><creator>Wentworth, Deborah</creator><creator>Babiker, Abdel G.</creator><creator>Davey, Victoria J.</creator><creator>Gelijns, Annetine C.</creator><creator>Matthews, Gail V.</creator><creator>Thompson, B. Taylor</creator><creator>Lane, H. 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The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>35963234</pmid><doi>10.1016/j.medj.2022.07.003</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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subjects | COVID-19 - prevention & control COVID-19 - therapy COVID-19 Vaccines Humans Inpatients Randomized Controlled Trials as Topic Vaccination - methods |
title | Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO) |
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