Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO)

The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, diffic...

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Veröffentlicht in:Med (New York, N.Y. : Online) N.Y. : Online), 2022-08, Vol.3 (8), p.531-537
Hauptverfasser: Mylonakis, Eleftherios, Lutaakome, Joseph, Jain, Mamta K., Rogers, Angela J., Moltó, José, Benet, Susana, Mourad, Ahmad, Files, D. Clark, Mugerwa, Henry, Kityo, Cissy, Kiweewa, Francis, Nalubega, Mary Grace, Kitonsa, Jonathan, Nabenkema, Evelyn, Murray, Daniel D., Braun, Dominique, Kamel, Dena, Higgs, Elizabeth S., Hatlen, Timothy J., Kan, Virginia L., Sanchez, Adriana, Tierney, John, Denner, Eileen, Wentworth, Deborah, Babiker, Abdel G., Davey, Victoria J., Gelijns, Annetine C., Matthews, Gail V., Thompson, B. Taylor, Lane, H. Clifford, Neaton, James D., Lundgren, Jens D.
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container_issue 8
container_start_page 531
container_title Med (New York, N.Y. : Online)
container_volume 3
creator Mylonakis, Eleftherios
Lutaakome, Joseph
Jain, Mamta K.
Rogers, Angela J.
Moltó, José
Benet, Susana
Mourad, Ahmad
Files, D. Clark
Mugerwa, Henry
Kityo, Cissy
Kiweewa, Francis
Nalubega, Mary Grace
Kitonsa, Jonathan
Nabenkema, Evelyn
Murray, Daniel D.
Braun, Dominique
Kamel, Dena
Higgs, Elizabeth S.
Hatlen, Timothy J.
Kan, Virginia L.
Sanchez, Adriana
Tierney, John
Denner, Eileen
Wentworth, Deborah
Babiker, Abdel G.
Davey, Victoria J.
Gelijns, Annetine C.
Matthews, Gail V.
Thompson, B. Taylor
Lane, H. Clifford
Neaton, James D.
Lundgren, Jens D.
description The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus. The protection provided by natural versus hybrid immunity from COVID-19 is unclear. We reflect on the challenges from trying to conduct a randomized post-SARS-CoV-2 infection vaccination trial study with rapidly evolving scientific data, vaccination guidelines, varying international policies, difficulties with vaccine availability, vaccine hesitancy, and a constantly evolving virus.
doi_str_mv 10.1016/j.medj.2022.07.003
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subjects COVID-19 - prevention & control
COVID-19 - therapy
COVID-19 Vaccines
Humans
Inpatients
Randomized Controlled Trials as Topic
Vaccination - methods
title Lessons from an international trial evaluating vaccination strategies for recovered inpatients with COVID-19 (VATICO)
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