HIV Pre-exposure Prophylaxis Implant Stated Preferences and Priorities: Results of a Discrete Choice Experiment Among Women and Adolescent Girls in Gauteng Province, South Africa
For adolescent girls (AG) and young women (YW), adherence barriers may limit the effectiveness of daily oral HIV pre-exposure prophylaxis (PrEP). Due to its low-burden and long-lasting product attributes, PrEP implants could remove some of the critical adherence barriers of oral PrEP products for in...
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| Veröffentlicht in: | AIDS and behavior 2022-09, Vol.26 (9), p.3099-3109 |
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| creator | Little, Kristen M. Flomen, Lola Hanif, Homaira Anderson, Sharon M. Thurman, Andrea R. Clark, Meredith R. Doncel, Gustavo F. |
| description | For adolescent girls (AG) and young women (YW), adherence barriers may limit the effectiveness of daily oral HIV pre-exposure prophylaxis (PrEP). Due to its low-burden and long-lasting product attributes, PrEP implants could remove some of the critical adherence barriers of oral PrEP products for individuals at risk of HIV. To explore stated preferences for a long-acting PrEP implant, we conducted a quantitative survey and discrete choice experiment with AG (ages 15–17), YW (18–34), and female sex workers (FSW; ≥ 18) in Gauteng Province, South Africa. We completed 600 quantitative surveys across the three subgroups of women. Respondents stated preference for an implant that provided longer HIV protection (24 months versus 6 months) and required a single insertion. They stated that they preferred a biodegradable implant that could be removed within 1 month of insertion. Respondents had no preference for a particular insertion location. Overall, 78% of respondents said they would be likely (33%) or very likely (45%) to use a PrEP implant were one available, with the majority (82%) stating preference for a product that would provide dual protection against HIV and unintended pregnancies. To reduce their risk of HIV, AG, YW, and FSW in our survey reported a strong willingness to use long-acting, highly-effective, dissolvable PrEP implants. |
| doi_str_mv | 10.1007/s10461-022-03658-w |
| format | Article |
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Due to its low-burden and long-lasting product attributes, PrEP implants could remove some of the critical adherence barriers of oral PrEP products for individuals at risk of HIV. To explore stated preferences for a long-acting PrEP implant, we conducted a quantitative survey and discrete choice experiment with AG (ages 15–17), YW (18–34), and female sex workers (FSW; ≥ 18) in Gauteng Province, South Africa. We completed 600 quantitative surveys across the three subgroups of women. Respondents stated preference for an implant that provided longer HIV protection (24 months versus 6 months) and required a single insertion. They stated that they preferred a biodegradable implant that could be removed within 1 month of insertion. Respondents had no preference for a particular insertion location. Overall, 78% of respondents said they would be likely (33%) or very likely (45%) to use a PrEP implant were one available, with the majority (82%) stating preference for a product that would provide dual protection against HIV and unintended pregnancies. To reduce their risk of HIV, AG, YW, and FSW in our survey reported a strong willingness to use long-acting, highly-effective, dissolvable PrEP implants.</description><identifier>ISSN: 1090-7165</identifier><identifier>EISSN: 1573-3254</identifier><identifier>DOI: 10.1007/s10461-022-03658-w</identifier><identifier>PMID: 35360893</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adolescence ; Adolescent girls ; Adolescents ; Biodegradability ; Biodegradation ; Disease prevention ; Girls ; Health Psychology ; HIV ; Human immunodeficiency virus ; Implants ; Infectious Diseases ; Insertion ; Medicine ; Medicine & Public Health ; Original Paper ; Polls & surveys ; Preferences ; Prophylaxis ; Prostitution ; Protection ; Public Health ; Sex workers ; Sexually transmitted diseases ; STD ; Subgroups ; Surveys ; Teenagers ; Transplants & implants ; Unwanted pregnancy ; Women ; Womens health ; Young women</subject><ispartof>AIDS and behavior, 2022-09, Vol.26 (9), p.3099-3109</ispartof><rights>The Author(s) 2022</rights><rights>2022. The Author(s).</rights><rights>The Author(s) 2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). 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Due to its low-burden and long-lasting product attributes, PrEP implants could remove some of the critical adherence barriers of oral PrEP products for individuals at risk of HIV. To explore stated preferences for a long-acting PrEP implant, we conducted a quantitative survey and discrete choice experiment with AG (ages 15–17), YW (18–34), and female sex workers (FSW; ≥ 18) in Gauteng Province, South Africa. We completed 600 quantitative surveys across the three subgroups of women. Respondents stated preference for an implant that provided longer HIV protection (24 months versus 6 months) and required a single insertion. They stated that they preferred a biodegradable implant that could be removed within 1 month of insertion. Respondents had no preference for a particular insertion location. Overall, 78% of respondents said they would be likely (33%) or very likely (45%) to use a PrEP implant were one available, with the majority (82%) stating preference for a product that would provide dual protection against HIV and unintended pregnancies. To reduce their risk of HIV, AG, YW, and FSW in our survey reported a strong willingness to use long-acting, highly-effective, dissolvable PrEP implants.</description><subject>Adolescence</subject><subject>Adolescent girls</subject><subject>Adolescents</subject><subject>Biodegradability</subject><subject>Biodegradation</subject><subject>Disease prevention</subject><subject>Girls</subject><subject>Health Psychology</subject><subject>HIV</subject><subject>Human immunodeficiency virus</subject><subject>Implants</subject><subject>Infectious Diseases</subject><subject>Insertion</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Original Paper</subject><subject>Polls & surveys</subject><subject>Preferences</subject><subject>Prophylaxis</subject><subject>Prostitution</subject><subject>Protection</subject><subject>Public Health</subject><subject>Sex workers</subject><subject>Sexually transmitted diseases</subject><subject>STD</subject><subject>Subgroups</subject><subject>Surveys</subject><subject>Teenagers</subject><subject>Transplants & implants</subject><subject>Unwanted pregnancy</subject><subject>Women</subject><subject>Womens health</subject><subject>Young 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>AIDS and behavior</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Little, Kristen M.</au><au>Flomen, Lola</au><au>Hanif, Homaira</au><au>Anderson, Sharon M.</au><au>Thurman, Andrea R.</au><au>Clark, Meredith R.</au><au>Doncel, Gustavo F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>HIV Pre-exposure Prophylaxis Implant Stated Preferences and Priorities: Results of a Discrete Choice Experiment Among Women and Adolescent Girls in Gauteng Province, South Africa</atitle><jtitle>AIDS and behavior</jtitle><stitle>AIDS Behav</stitle><addtitle>AIDS Behav</addtitle><date>2022-09-01</date><risdate>2022</risdate><volume>26</volume><issue>9</issue><spage>3099</spage><epage>3109</epage><pages>3099-3109</pages><issn>1090-7165</issn><eissn>1573-3254</eissn><abstract>For adolescent girls (AG) and young women (YW), adherence barriers may limit the effectiveness of daily oral HIV pre-exposure prophylaxis (PrEP). 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Overall, 78% of respondents said they would be likely (33%) or very likely (45%) to use a PrEP implant were one available, with the majority (82%) stating preference for a product that would provide dual protection against HIV and unintended pregnancies. To reduce their risk of HIV, AG, YW, and FSW in our survey reported a strong willingness to use long-acting, highly-effective, dissolvable PrEP implants.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>35360893</pmid><doi>10.1007/s10461-022-03658-w</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-4173-6167</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescence Adolescent girls Adolescents Biodegradability Biodegradation Disease prevention Girls Health Psychology HIV Human immunodeficiency virus Implants Infectious Diseases Insertion Medicine Medicine & Public Health Original Paper Polls & surveys Preferences Prophylaxis Prostitution Protection Public Health Sex workers Sexually transmitted diseases STD Subgroups Surveys Teenagers Transplants & implants Unwanted pregnancy Women Womens health Young women |
| title | HIV Pre-exposure Prophylaxis Implant Stated Preferences and Priorities: Results of a Discrete Choice Experiment Among Women and Adolescent Girls in Gauteng Province, South Africa |
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