Drug-Loaded Chitosan Scaffolds for Periodontal Tissue Regeneration

Chitosan is a natural anionic polysaccharide with a changeable architecture and an abundance of functional groups; in addition, it can be converted into various shapes and sizes, making it appropriate for a variety of applications. This article examined and summarized current developments in chitosa...

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Veröffentlicht in:Polymers 2022-08, Vol.14 (15), p.3192
Hauptverfasser: Atia, Gamal Abdel Nasser, Shalaby, Hany K, Zehravi, Mehrukh, Ghobashy, Mohamed Mohamady, Attia, Hager Abdel Nasser, Ahmad, Zubair, Khan, Farhat S, Dey, Abhijit, Mukerjee, Nobendu, Alexiou, Athanasios, Rahman, Md Habibur, Klepacka, Joanna, Najda, Agnieszka
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container_issue 15
container_start_page 3192
container_title Polymers
container_volume 14
creator Atia, Gamal Abdel Nasser
Shalaby, Hany K
Zehravi, Mehrukh
Ghobashy, Mohamed Mohamady
Attia, Hager Abdel Nasser
Ahmad, Zubair
Khan, Farhat S
Dey, Abhijit
Mukerjee, Nobendu
Alexiou, Athanasios
Rahman, Md Habibur
Klepacka, Joanna
Najda, Agnieszka
description Chitosan is a natural anionic polysaccharide with a changeable architecture and an abundance of functional groups; in addition, it can be converted into various shapes and sizes, making it appropriate for a variety of applications. This article examined and summarized current developments in chitosan-based materials, with a focus on the modification of chitosan, and presented an abundance of information about the fabrication and use of chitosan-derived products in periodontal regeneration. Numerous preparation and modification techniques for enhancing chitosan performance, as well as the uses of chitosan and its metabolites, were reviewed critically and discussed in depth in this study. Chitosan-based products may be formed into different shapes and sizes, considering fibers, nanostructures, gels, membranes, and hydrogels. Various drug-loaded chitosan devices were discussed regarding periodontal regeneration.
doi_str_mv 10.3390/polym14153192
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source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central
subjects Biocompatibility
Biodegradation
Biomedical materials
Bone surgery
Chitosan
Collagen
Drug delivery systems
Drug resistance
Fibroblasts
Functional groups
Hydrogels
Manufacturers
Medicine
Metabolites
Nanoparticles
Permeability
Polymers
Polysaccharides
Regeneration (physiology)
Review
Solvents
Tissue engineering
title Drug-Loaded Chitosan Scaffolds for Periodontal Tissue Regeneration
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