Drug-Loaded Chitosan Scaffolds for Periodontal Tissue Regeneration
Chitosan is a natural anionic polysaccharide with a changeable architecture and an abundance of functional groups; in addition, it can be converted into various shapes and sizes, making it appropriate for a variety of applications. This article examined and summarized current developments in chitosa...
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Veröffentlicht in: | Polymers 2022-08, Vol.14 (15), p.3192 |
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creator | Atia, Gamal Abdel Nasser Shalaby, Hany K Zehravi, Mehrukh Ghobashy, Mohamed Mohamady Attia, Hager Abdel Nasser Ahmad, Zubair Khan, Farhat S Dey, Abhijit Mukerjee, Nobendu Alexiou, Athanasios Rahman, Md Habibur Klepacka, Joanna Najda, Agnieszka |
description | Chitosan is a natural anionic polysaccharide with a changeable architecture and an abundance of functional groups; in addition, it can be converted into various shapes and sizes, making it appropriate for a variety of applications. This article examined and summarized current developments in chitosan-based materials, with a focus on the modification of chitosan, and presented an abundance of information about the fabrication and use of chitosan-derived products in periodontal regeneration. Numerous preparation and modification techniques for enhancing chitosan performance, as well as the uses of chitosan and its metabolites, were reviewed critically and discussed in depth in this study. Chitosan-based products may be formed into different shapes and sizes, considering fibers, nanostructures, gels, membranes, and hydrogels. Various drug-loaded chitosan devices were discussed regarding periodontal regeneration. |
doi_str_mv | 10.3390/polym14153192 |
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Various drug-loaded chitosan devices were discussed regarding periodontal regeneration.</description><identifier>ISSN: 2073-4360</identifier><identifier>EISSN: 2073-4360</identifier><identifier>DOI: 10.3390/polym14153192</identifier><identifier>PMID: 35956708</identifier><language>eng</language><publisher>Switzerland: MDPI AG</publisher><subject>Biocompatibility ; Biodegradation ; Biomedical materials ; Bone surgery ; Chitosan ; Collagen ; Drug delivery systems ; Drug resistance ; Fibroblasts ; Functional groups ; Hydrogels ; Manufacturers ; Medicine ; Metabolites ; Nanoparticles ; Permeability ; Polymers ; Polysaccharides ; Regeneration (physiology) ; Review ; Solvents ; Tissue engineering</subject><ispartof>Polymers, 2022-08, Vol.14 (15), p.3192</ispartof><rights>2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). 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Various drug-loaded chitosan devices were discussed regarding periodontal regeneration.</description><subject>Biocompatibility</subject><subject>Biodegradation</subject><subject>Biomedical materials</subject><subject>Bone surgery</subject><subject>Chitosan</subject><subject>Collagen</subject><subject>Drug delivery systems</subject><subject>Drug resistance</subject><subject>Fibroblasts</subject><subject>Functional groups</subject><subject>Hydrogels</subject><subject>Manufacturers</subject><subject>Medicine</subject><subject>Metabolites</subject><subject>Nanoparticles</subject><subject>Permeability</subject><subject>Polymers</subject><subject>Polysaccharides</subject><subject>Regeneration (physiology)</subject><subject>Review</subject><subject>Solvents</subject><subject>Tissue engineering</subject><issn>2073-4360</issn><issn>2073-4360</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpdkd9LwzAQx4Mobsw9-ioFX3ypJk2aNC-Czp8wUHQ-hzS9bh1dM5NW2H9vxubYvIe7g_vclzu-CJ0TfE2pxDdLW68WhJGUEpkcoX6CBY0Z5fh4r--hofdzHIKlnBNxino0lSkXOOuj-wfXTeOx1QUU0WhWtdbrJvo0uixtXfiotC56B1fZwjatrqNJ5X0H0QdMoQGn28o2Z-ik1LWH4bYO0NfT42T0Eo_fnl9Hd-PYsIy0MS9wSijIcAYnlBuqE2CyEFyAIHlGcKpzxnHOMpwAD1QJzBQmF3lGExJWBuh2o7vs8gUUBprW6VotXbXQbqWsrtThpKlmamp_lKSC4EwGgautgLPfHfhWLSpvoK51A7bzKhE4IRmWLAvo5T90bjvXhPfWFBZ8nQMVbyjjrPcOyt0xBKu1QerAoMBf7H-wo__soL_mr4tV</recordid><startdate>20220805</startdate><enddate>20220805</enddate><creator>Atia, Gamal Abdel Nasser</creator><creator>Shalaby, Hany K</creator><creator>Zehravi, Mehrukh</creator><creator>Ghobashy, Mohamed Mohamady</creator><creator>Attia, Hager Abdel Nasser</creator><creator>Ahmad, Zubair</creator><creator>Khan, Farhat S</creator><creator>Dey, Abhijit</creator><creator>Mukerjee, Nobendu</creator><creator>Alexiou, Athanasios</creator><creator>Rahman, Md Habibur</creator><creator>Klepacka, Joanna</creator><creator>Najda, Agnieszka</creator><general>MDPI AG</general><general>MDPI</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>KB.</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7040-8496</orcidid><orcidid>https://orcid.org/0000-0001-6099-5693</orcidid><orcidid>https://orcid.org/0000-0002-5750-0802</orcidid><orcidid>https://orcid.org/0000-0001-5871-635X</orcidid><orcidid>https://orcid.org/0000-0002-1185-8884</orcidid><orcidid>https://orcid.org/0000-0003-0968-1423</orcidid><orcidid>https://orcid.org/0000-0002-7129-7003</orcidid><orcidid>https://orcid.org/0000-0002-2206-7236</orcidid></search><sort><creationdate>20220805</creationdate><title>Drug-Loaded Chitosan Scaffolds for Periodontal Tissue Regeneration</title><author>Atia, Gamal Abdel Nasser ; 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subjects | Biocompatibility Biodegradation Biomedical materials Bone surgery Chitosan Collagen Drug delivery systems Drug resistance Fibroblasts Functional groups Hydrogels Manufacturers Medicine Metabolites Nanoparticles Permeability Polymers Polysaccharides Regeneration (physiology) Review Solvents Tissue engineering |
title | Drug-Loaded Chitosan Scaffolds for Periodontal Tissue Regeneration |
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