Essential Role and Mechanism of Transcription-coupled DNA Repair in Bacteria

Transcription-coupled DNA repair (TCR) is presumed to be a minor sub-pathway of nucleotide excision repair (NER) in bacteria. Global genomic repair (GGR) is thought to perform the bulk of repair independently of transcription. TCR is also believed to be mediated exclusively by Mfd – a DNA translocas...

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Veröffentlicht in:Nature (London) 2022-03, Vol.604 (7904), p.152-159
Hauptverfasser: Bharati, Binod K., Gowder, Manjunath, Zheng, Fangfang, Alzoubi, Khaled, Svetlov, Vladimir, Kamarthapu, Venu, Weaver, Jacob W., Epshtein, Vitaly, Vasilyev, Nikita, Shen, Liqiang, Zhang, Yu, Nudler, Evgeny
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Sprache:eng
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