Cortico-striatal circuits: Novel therapeutic targets for substance use disorders

Abstract It is widely believed that substance use disorder (SUD) results from both pre-alterations (vulnerability) and/or post-alterations (drug effects) on cortico-striatal circuits. These circuits are essential for cognitive control, motivation, reward dependent learning, and emotional processing....

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Veröffentlicht in:	Brain research 2015-12, Vol.1628 (Pt A), p.186-198
Hauptverfasser:	Kravitz, Alexxai V, Tomasi, Dardo, LeBlanc, Kimberly H, Baler, Ruben, Volkow, Nora D, Bonci, Antonello, Ferré, Sergi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cerebral Cortex - drug effects Cerebral Cortex - physiopathology Corpus Striatum - drug effects Corpus Striatum - physiopathology Cortico-striatal DBS fMRI Frontal cortex Humans Neural Pathways - drug effects Neural Pathways - physiopathology Neurology Substance use disorder Substance-Related Disorders - physiopathology Substance-Related Disorders - therapy TMS
Online-Zugang:	Volltext
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