Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non-Muscle-Invasive Bladder Cancer

High-grade T1 (HGT1) bladder cancer is the highest risk subtype of non-muscle-invasive bladder cancer with unpredictable outcome and poorly understood risk factors. Here, we examined the association of somatic mutation profiles with nonrecurrent disease (GO, good outcome), recurrence (R), or progres...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2020-10, Vol.80 (20), p.4476-4486
Hauptverfasser:	Bellmunt, Joaquim, Kim, Jaegil, Reardon, Brendan, Perera-Bel, Júlia, Orsola, Anna, Rodriguez-Vida, Alejo, Wankowicz, Stephanie A, Bowden, Michaela, Barletta, Justine A, Morote, Juan, de Torres, Inés, Juanpere, Nuria, Lloreta-Trull, Josep, Hernandez, Silvia, Mouw, Kent W, Taplin, Mary-Ellen, Cejas, Paloma, Long, Henry W, Van Allen, Eliezer M, Getz, Gad, Kwiatkowski, David J
Format:	Artikel
Sprache:	eng
Schlagworte:	Cyclin E - genetics Cyclin-Dependent Kinase Inhibitor p16 - genetics Female Follow-Up Studies Gene Dosage Humans Male Muscles - pathology Mutation Neoplasm Recurrence, Local - pathology Oncogene Proteins - genetics Tumor Suppressor Protein p53 - genetics Urinary Bladder Neoplasms - genetics Urinary Bladder Neoplasms - mortality Urinary Bladder Neoplasms - pathology Xeroderma Pigmentosum Group D Protein - genetics
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