Helicobacter pylori Modulated Host Immunity in Gastric Cancer Patients With S-1 Adjuvant Chemotherapy

Abstract Background Paradoxically, Helicobacter pylori–positive (HP+) advanced gastric cancer patients have a better prognosis than those who are HP–negative (HP-). Immunologic and statistical analyses can be used to verify whether systemic mechanisms modulated by HP are involved in this more favora...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2022-08, Vol.114 (8), p.1149-1158
Hauptverfasser:	Koizumi, Yuka, Ahmad, Sheny, Ikeda, Miyuki, Yashima-Abo, Akiko, Espina, Ginny, Sugimoto, Ryo, Sugai, Tamotsu, Iwaya, Takeshi, Tamura, Gen, Koeda, Keisuke, Liotta, Lance A, Takahashi, Fumiaki, Nishizuka, Satoshi S
Format:	Artikel
Sprache:	eng
Schlagworte:	B7-H1 Antigen - metabolism Cancer CD4 antigen CD8 antigen Chemotherapy Chemotherapy, Adjuvant Confidence intervals Gastrectomy Gastric cancer Hazard identification Health hazards Helicobacter pylori Humans Immune system Medical prognosis Microsatellite instability Mismatch repair Neoplasm Recurrence, Local - pathology PD-L1 protein Prognosis Regression analysis Retrospective Studies Stability analysis Statistical analysis Stomach Neoplasms - drug therapy Stomach Neoplasms - metabolism Stomach Neoplasms - surgery Subgroups Survival
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