Persistence of Chemotherapy-Induced Peripheral Neuropathy Despite Vincristine Reduction in Childhood B-Acute Lymphoblastic Leukemia

Abstract Background Children with B-acute lymphoblastic leukemia (B-ALL) are at risk for chemotherapy-induced peripheral neuropathy (CIPN). Children’s Oncology Group AALL0932 randomized reduction in vincristine and dexamethasone (every 4 weeks vs 12 weeks during maintenance in the average-risk subse...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2022-08, Vol.114 (8), p.1167-1175
Hauptverfasser:	Rodwin, Rozalyn L, Kairalla, John A, Hibbitts, Emily, Devidas, Meenakshi, Whitley, Moira K, Mohrmann, Caroline E, Schore, Reuven J, Raetz, Elizabeth, Winick, Naomi J, Hunger, Stephen P, Loh, Mignon L, Hockenberry, Marilyn J, Angiolillo, Anne L, Ness, Kirsten K, Kadan-Lottick, Nina S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute lymphoblastic leukemia Ankle Antineoplastic Agents - therapeutic use Chemotherapy Child Child, Preschool Children Data collection Dexamethasone Dexamethasone - therapeutic use Evaluation Female Hand Strength Humans Leukemia Longitudinal Studies Maintenance Male Pediatrics Peripheral Nervous System Diseases - chemically induced Peripheral neuropathy Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Quality of Life Range of motion Reduction Vibration Vincristine Vincristine - adverse effects Walking
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