Prospectively Isolated Tetraspanin+ Neoblasts Are Adult Pluripotent Stem Cells Underlying Planaria Regeneration

Proliferating cells known as neoblasts include pluripotent stem cells (PSCs) that sustain tissue homeostasis and regeneration of lost body parts in planarians. However, the lack of markers to prospectively identify and isolate these adult PSCs has significantly hampered their characterization. We us...

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Veröffentlicht in:	Cell 2018-06, Vol.173 (7), p.1593-1608.e20
Hauptverfasser:	Zeng, An, Li, Hua, Guo, Longhua, Gao, Xin, McKinney, Sean, Wang, Yongfu, Yu, Zulin, Park, Jungeun, Semerad, Craig, Ross, Eric, Cheng, Li-Chun, Davies, Erin, Lei, Kai, Wang, Wei, Perera, Anoja, Hall, Kate, Peak, Allison, Box, Andrew, Sánchez Alvarado, Alejandro
Format:	Artikel
Sprache:	eng
Schlagworte:	planaria pluripotent prospective isolation regeneration single cell transplantation stem cells tetraspanin
Online-Zugang:	Volltext
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