Genomic analysis of 1,25-dihydroxyvitamin D3 action in mouse intestine reveals compartment and segment-specific gene regulatory effects

1,25-dihydroxyvitamin D (VD) regulates intestinal calcium absorption in the small intestine (SI) and also reduces risk of colonic inflammation and cancer. However, the intestine compartment-specific target genes of VD signaling are unknown. Here, we examined VD action across three functional compart...

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Veröffentlicht in:	The Journal of biological chemistry 2022-08, Vol.298 (8), p.102213-102213, Article 102213
Hauptverfasser:	Aita, Rohit, Aldea, Dennis, Hassan, Sohaib, Hur, Joseph, Pellon-Cardenas, Oscar, Cohen, Evan, Chen, Lei, Shroyer, Noah, Christakos, Sylvia, Verzi, Michael P., Fleet, James C.
Format:	Artikel
Sprache:	eng
Schlagworte:	colon genomics intestinal epithelium small intestine steroid hormone receptor transcription transcription enhancer transcription factor vitamin D vitamin D receptor
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