Genomics and Epigenomics of Medullary Thyroid Carcinoma: From Sporadic Disease to Familial Manifestations

Our understanding of the genomics and epigenomics of medullary thyroid carcinoma (MTC) has advanced since the initial recognition of RET as a driver of MTC tumorigenesis in familial MTC. We now have insight into the frequency and prognostic significance of specific RET mutations in sporadic MTC. For...

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Veröffentlicht in:	Endocrine pathology 2021-03, Vol.32 (1), p.35-43
Hauptverfasser:	Barletta, Justine A., Nosé, Vânia, Sadow, Peter M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Endocrinology Epigenetics Genomics Medicine Medicine & Public Health Mutation Oncology Pathology Patients Thyroid cancer Thyroid carcinoma Tumorigenesis
Online-Zugang:	Volltext
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