Optimization of ultrasonic extraction by response surface methodology combined with ultrafast liquid chromatography–ultraviolet method for determination of four iridoids in Gentiana rigescens

Gentiana rigescens is a rich source of iridoids and is commonly used as a folk medicine for treatment of hepatitis and cholecystitis for over 1000 years. A rapid ultrafast liquid chromatography–ultraviolet method was developed for simultaneous determination of four major iridoid glycosides in G. rig...

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Veröffentlicht in:	Journal of food and drug analysis 2015-09, Vol.23 (3), p.529-537
Hauptverfasser:	Pan, Yu, Zhang, Ji, Shen, Tao, Zuo, Zhi-Tian, Jin, Hang, Wang, Yuan-Zhong, Li, Wan-Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetonitrile Acids Cholecystitis Chromatography Design optimization Experiments Flow velocity Formic acid Gentiana rigescens Glycosides Hepatitis Herbal medicine iridoid glycosides Liquid chromatography Mathematical models Methods Original Quality Raw materials Response surface methodology ultrafast liquid chromatography–ultraviolet ultrasonic assisted extraction Variables Variance analysis
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