Selective reaction monitoring approach using structure-defined synthetic glycopeptides for validating glycopeptide biomarkers pre-determined by bottom-up glycoproteomics

Clusterin is a heavily glycosylated protein that is upregulated in various cancer and neurological diseases. The findings by the Hancock and Iliopoulos group that levels of the tryptic glycopeptide derived from plasma clusterin, 372 Leu-Ala-Asn-Leu-Thr-Gln-Gly-Glu-Asp-Gln-Tyr-Tyr-Leu-Arg 385 with a...

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Veröffentlicht in:	RSC advances 2022-08, Vol.12 (33), p.21385-21393
Hauptverfasser:	Shiratori, Kouta, Yokoi, Yasuhiro, Wakui, Hajime, Hirane, Nozomi, Otaki, Michiru, Hinou, Hiroshi, Yoneyama, Tohru, Hatakeyama, Shingo, Kimura, Satoshi, Ohyama, Chikara, Nishimura, Shin-Ichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Biomarkers Cancer Chemistry Glycan Glycopeptides Monitoring Neurological diseases
Online-Zugang:	Volltext
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