The MNU Plus Testosterone Rat Model of Prostate Carcinogenesis

Animal models of prostate cancer are essential to identify chemopreventive treatments against this major male malignancy. The N-methyl-N-nitrosourea (MNU) plus testosterone rat model of prostate carcinogenesis is a reliable animal model that recapitulates human prostate cancer in many respects and h...

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Veröffentlicht in:	Toxicologic pathology 2022-06, Vol.50 (4), p.478-496
Hauptverfasser:	Bosland, Maarten C., Schlicht, Michael J., Horton, Lori, McCormick, David L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - chemically induced Animals Carcinogenesis - chemically induced Disease Models, Animal Humans Male Prostate Prostatic Neoplasms - chemically induced Rats Rats, Inbred F344 Rats, Wistar Reproducibility of Results Testosterone
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