Brain Structure Among Middle-aged and Older Adults With Long-standing Type 1 Diabetes in the DCCT/EDIC Study

Individuals with type 1 diabetes mellitus (T1DM) are living to ages when neuropathological changes are increasingly evident. We hypothesized that middle-aged and older adults with long-standing T1DM will show abnormal brain structure in comparison with control subjects without diabetes. MRI was used...

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Veröffentlicht in:	Diabetes care 2022-08, Vol.45 (8), p.1779-1787
Hauptverfasser:	Jacobson, Alan M, Braffett, Barbara H, Erus, Guray, Ryan, Christopher M, Biessels, Geert J, Luchsinger, José A, Bebu, Ionut, Gubitosi-Klug, Rose A, Desiderio, Lisa, Lorenzi, Gayle M, Trapani, Victoria R, Lachin, John M, Bryan, R Nick, Habes, Mohamad, Nasrallah, Ilya M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Aged Aging Anisotropy Assessments Blood pressure Brain Brain - pathology Canada Cerebrovascular disease Cognitive ability Complications Diabetes Diabetes Complications - complications Diabetes mellitus Diabetes mellitus (insulin dependent) Diabetes Mellitus, Type 1 - complications Epidemiology Epidemiology/Health Services Research Equivalence Glycated Hemoglobin - analysis Humans Hypoglycemia Lipids Magnetic resonance imaging Middle age Middle Aged Neuropathology Older people Risk Factors Substantia alba Substantia grisea Ventricle Ventricles (cerebral)
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