Phagocytic microglia and macrophages in brain injury and repair

Aims Phagocytosis is the cellular digestion of extracellular particles, such as pathogens and dying cells, and is a key element in the evolution of central nervous system (CNS) disorders. Microglia and macrophages are the professional phagocytes of the CNS. By clearing toxic cellular debris and resh...

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Veröffentlicht in:	CNS neuroscience & therapeutics 2022-09, Vol.28 (9), p.1279-1293
Hauptverfasser:	Yu, Fang, Wang, Yangfan, Stetler, Anne R., Leak, Rehana K., Hu, Xiaoming, Chen, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	acute brain injury Adenosine Alzheimer's disease Brain Brain Injuries Brain injury brain repair Central nervous system Central Nervous System Diseases Death & dying Endoplasmic reticulum Extracellular matrix Humans Inflammation Kinases Leukocytes (neutrophilic) Macrophages Macrophages - physiology Microglia Microglia - physiology microglia/macrophage Myelin Neurodegeneration Neurogenesis Neurological disorders Neurons Phagocytes Phagocytosis Proteins Recovery of function Review Reviews Synaptogenesis Traumatic brain injury
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