Transmission of SARS-CoV-2 among children and staff in German daycare centres
In daycare centres, the close contact of children with other children and employees favours the transmission of infections. The majority of children
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| Veröffentlicht in: | Epidemiology and infection 2022-07, Vol.150, p.e141, Article e141 |
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| creator | Loss, Julika Wurm, Juliane Varnaccia, Gianni Schienkiewitz, Anja Iwanowski, Helena Loer, Anne-Kathrin Mareike Allen, Jennifer Wess, Barbara Schaffrath Rosario, Angelika Damerow, Stefan Kuttig, Tim Perlitz, Hanna Hornbacher, Anselm Finkel, Bianca Krause, Carolin Wormsbächer, Jan Sandoni, Anna Kubisch, Ulrike Eggers, Kiara Nitsche, Andreas Radonic, Aleksandar Trappe, Kathrin Drechsel, Oliver Klaper, Kathleen Franke, Andrea Hüther, Antje Buchholz, Udo Haas, Walter Wieler, Lothar H. Jordan, Susanne |
| description | In daycare centres, the close contact of children with other children and employees favours the transmission of infections. The majority of children |
| doi_str_mv | 10.1017/S0950268822001194 |
| format | Article |
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The majority of children <6 years attend daycare programmes in Germany, but the role of daycare centres in the SARS-CoV-2 pandemic is unclear. We investigated the transmission risk in daycare centres and the spread of SARS-CoV-2 to associated households. 30 daycare groups with at least one recent laboratory-confirmed SARS-CoV-2 case were enrolled in the study (10/2020–06/2021). Close contact persons within daycare and households were examined over a 12-day period (repeated SARS-CoV-2 PCR tests, genetic sequencing of viruses, symptom diary). Households were interviewed to gain comprehensive information on each outbreak. We determined primary cases for all daycare groups. The number of secondary cases varied considerably between daycare groups. The pooled secondary attack rate (SAR) across all 30 daycare centres was 9.6%. The SAR tended to be higher when the Alpha variant was detected (15.9% vs. 5.1% with evidence of wild type). The household SAR was 53.3%. Exposed daycare children were less likely to get infected with SARS-CoV-2 than employees (7.7% vs. 15.5%). Containment measures in daycare programmes are critical to reduce SARS-CoV-2 transmission, especially to avoid spread to associated households.</description><identifier>ISSN: 0950-2688</identifier><identifier>ISSN: 1469-4409</identifier><identifier>EISSN: 1469-4409</identifier><identifier>DOI: 10.1017/S0950268822001194</identifier><identifier>PMID: 35912971</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Child ; Children ; Children & youth ; Coronaviruses ; COVID-19 ; COVID-19 - epidemiology ; Day care centers ; Daycare ; Disease Outbreaks ; Disease transmission ; Gene sequencing ; Households ; Humans ; Laboratories ; Longitudinal studies ; Original Paper ; Pandemics ; Questionnaires ; SARS-CoV-2 ; Severe acute respiratory syndrome ; Severe acute respiratory syndrome coronavirus 2 ; Ventilation ; Viral diseases ; Viruses</subject><ispartof>Epidemiology and infection, 2022-07, Vol.150, p.e141, Article e141</ispartof><rights>Copyright © The Author(s), 2022. Published by Cambridge University Press</rights><rights>Copyright © The Author(s), 2022. Published by Cambridge University Press. This work is licensed under the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/ (the “License”). 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Infect</addtitle><description>In daycare centres, the close contact of children with other children and employees favours the transmission of infections. The majority of children <6 years attend daycare programmes in Germany, but the role of daycare centres in the SARS-CoV-2 pandemic is unclear. We investigated the transmission risk in daycare centres and the spread of SARS-CoV-2 to associated households. 30 daycare groups with at least one recent laboratory-confirmed SARS-CoV-2 case were enrolled in the study (10/2020–06/2021). Close contact persons within daycare and households were examined over a 12-day period (repeated SARS-CoV-2 PCR tests, genetic sequencing of viruses, symptom diary). Households were interviewed to gain comprehensive information on each outbreak. We determined primary cases for all daycare groups. The number of secondary cases varied considerably between daycare groups. The pooled secondary attack rate (SAR) across all 30 daycare centres was 9.6%. The SAR tended to be higher when the Alpha variant was detected (15.9% vs. 5.1% with evidence of wild type). The household SAR was 53.3%. Exposed daycare children were less likely to get infected with SARS-CoV-2 than employees (7.7% vs. 15.5%). Containment measures in daycare programmes are critical to reduce SARS-CoV-2 transmission, especially to avoid spread to associated households.</description><subject>Child</subject><subject>Children</subject><subject>Children & youth</subject><subject>Coronaviruses</subject><subject>COVID-19</subject><subject>COVID-19 - epidemiology</subject><subject>Day care centers</subject><subject>Daycare</subject><subject>Disease Outbreaks</subject><subject>Disease transmission</subject><subject>Gene sequencing</subject><subject>Households</subject><subject>Humans</subject><subject>Laboratories</subject><subject>Longitudinal studies</subject><subject>Original Paper</subject><subject>Pandemics</subject><subject>Questionnaires</subject><subject>SARS-CoV-2</subject><subject>Severe acute respiratory syndrome</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Ventilation</subject><subject>Viral 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Infect</addtitle><date>2022-07-08</date><risdate>2022</risdate><volume>150</volume><spage>e141</spage><pages>e141-</pages><artnum>e141</artnum><issn>0950-2688</issn><issn>1469-4409</issn><eissn>1469-4409</eissn><abstract>In daycare centres, the close contact of children with other children and employees favours the transmission of infections. The majority of children <6 years attend daycare programmes in Germany, but the role of daycare centres in the SARS-CoV-2 pandemic is unclear. We investigated the transmission risk in daycare centres and the spread of SARS-CoV-2 to associated households. 30 daycare groups with at least one recent laboratory-confirmed SARS-CoV-2 case were enrolled in the study (10/2020–06/2021). Close contact persons within daycare and households were examined over a 12-day period (repeated SARS-CoV-2 PCR tests, genetic sequencing of viruses, symptom diary). Households were interviewed to gain comprehensive information on each outbreak. 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| fulltext | fulltext |
| identifier | ISSN: 0950-2688 |
| ispartof | Epidemiology and infection, 2022-07, Vol.150, p.e141, Article e141 |
| issn | 0950-2688 1469-4409 1469-4409 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9343344 |
| source | MEDLINE; Cambridge Journals Open Access; DOAJ Directory of Open Access Journals; PubMed Central |
| subjects | Child Children Children & youth Coronaviruses COVID-19 COVID-19 - epidemiology Day care centers Daycare Disease Outbreaks Disease transmission Gene sequencing Households Humans Laboratories Longitudinal studies Original Paper Pandemics Questionnaires SARS-CoV-2 Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Ventilation Viral diseases Viruses |
| title | Transmission of SARS-CoV-2 among children and staff in German daycare centres |
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