Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency
Vitamin B12 deficiency is a multifactorial condition, with a wide range of clinical presentations from mild to severe anemia and anemia-related neurological deficits. Hemolysis is a unique cause but has increasingly been recognized lately as a possible B12 deficiency presentation. Our patient presen...
Gespeichert in:
| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2022-07, Vol.14 (7) |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | 7 |
| container_start_page | |
| container_title | Curēus (Palo Alto, CA) |
| container_volume | 14 |
| creator | Abdalla, ELMustafa Al-Sadi, Anas Fadul, Abdalla Ahmed, Ahmed H Musa, Muzamil |
| description | Vitamin B12 deficiency is a multifactorial condition, with a wide range of clinical presentations from mild to severe anemia and anemia-related neurological deficits. Hemolysis is a unique cause but has increasingly been recognized lately as a possible B12 deficiency presentation. Our patient presented with hemolytic anemia, for which extensive workup has excluded the common hemolysis etiologies. Therefore, it was attributed to B12 deficiency and improved significantly after treatment. Our case highlights the significance of this unusual presentation and its clinical implementation. |
| doi_str_mv | 10.7759/cureus.26507 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9340670</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2708646799</sourcerecordid><originalsourceid>FETCH-LOGICAL-c243t-4bd5661877cba2c8828c843987e88148ac9262d73433c5c9b1e8697767b294d73</originalsourceid><addsrcrecordid>eNpVkUlLBDEQhYMoKurNHxDwamu2znIR3BVEBZdrSGdqNNKdaNIZmH_v6IjoqYqqx6tXfAjtUnKgVGsOfc1QywGTLVEraJNRqRtNtVj902-gnVLeCCGUKEYUWUcbvDWMC6030eQ2xSYMQ42Ar-OY3cwVX3uX8RUMqZ-PwePjCENw-9hF_BRrqa7H9xkKxNGNIUWcpvgBZpABP4fRDSHik4YyfAbT4ANEP99Ga1PXF9j5qVvo6eL88fSqubm7vD49vmk8E3xsRDdppaRaKd855rVm2mvBjVagNRXaecMkmyguOPetNx0FLY1SUnXMiMV8Cx0tfd9rN8DEw9dDvX3PYXB5bpML9v8mhlf7kmbWcEGkIguDvR-DnD4qlNG-pZrjIrNlimgppDJmodpfqnxOpWSY_l6gxH5hsUss9hsL_wRAQX_P</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2708646799</pqid></control><display><type>article</type><title>Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency</title><source>PubMed Central Open Access</source><source>PubMed Central</source><creator>Abdalla, ELMustafa ; Al-Sadi, Anas ; Fadul, Abdalla ; Ahmed, Ahmed H ; Musa, Muzamil</creator><creatorcontrib>Abdalla, ELMustafa ; Al-Sadi, Anas ; Fadul, Abdalla ; Ahmed, Ahmed H ; Musa, Muzamil</creatorcontrib><description>Vitamin B12 deficiency is a multifactorial condition, with a wide range of clinical presentations from mild to severe anemia and anemia-related neurological deficits. Hemolysis is a unique cause but has increasingly been recognized lately as a possible B12 deficiency presentation. Our patient presented with hemolytic anemia, for which extensive workup has excluded the common hemolysis etiologies. Therefore, it was attributed to B12 deficiency and improved significantly after treatment. Our case highlights the significance of this unusual presentation and its clinical implementation.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.26507</identifier><identifier>PMID: 35923488</identifier><language>eng</language><publisher>Palo Alto: Cureus Inc</publisher><subject>Abdomen ; Anemia ; Asymptomatic ; Blood ; Case reports ; Cell division ; Dehydrogenases ; Dyspnea ; Hematology ; Hemoglobin ; Immunology ; Internal Medicine ; Neurology ; Pain ; Thyroid gland ; Veganism ; Vitamin B ; Vitamin deficiency</subject><ispartof>Curēus (Palo Alto, CA), 2022-07, Vol.14 (7)</ispartof><rights>Copyright © 2022, Abdalla et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Copyright © 2022, Abdalla et al. 2022 Abdalla et al.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c243t-4bd5661877cba2c8828c843987e88148ac9262d73433c5c9b1e8697767b294d73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340670/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9340670/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,315,728,781,785,886,27926,27927,53793,53795</link.rule.ids></links><search><creatorcontrib>Abdalla, ELMustafa</creatorcontrib><creatorcontrib>Al-Sadi, Anas</creatorcontrib><creatorcontrib>Fadul, Abdalla</creatorcontrib><creatorcontrib>Ahmed, Ahmed H</creatorcontrib><creatorcontrib>Musa, Muzamil</creatorcontrib><title>Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency</title><title>Curēus (Palo Alto, CA)</title><description>Vitamin B12 deficiency is a multifactorial condition, with a wide range of clinical presentations from mild to severe anemia and anemia-related neurological deficits. Hemolysis is a unique cause but has increasingly been recognized lately as a possible B12 deficiency presentation. Our patient presented with hemolytic anemia, for which extensive workup has excluded the common hemolysis etiologies. Therefore, it was attributed to B12 deficiency and improved significantly after treatment. Our case highlights the significance of this unusual presentation and its clinical implementation.</description><subject>Abdomen</subject><subject>Anemia</subject><subject>Asymptomatic</subject><subject>Blood</subject><subject>Case reports</subject><subject>Cell division</subject><subject>Dehydrogenases</subject><subject>Dyspnea</subject><subject>Hematology</subject><subject>Hemoglobin</subject><subject>Immunology</subject><subject>Internal Medicine</subject><subject>Neurology</subject><subject>Pain</subject><subject>Thyroid gland</subject><subject>Veganism</subject><subject>Vitamin B</subject><subject>Vitamin deficiency</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpVkUlLBDEQhYMoKurNHxDwamu2znIR3BVEBZdrSGdqNNKdaNIZmH_v6IjoqYqqx6tXfAjtUnKgVGsOfc1QywGTLVEraJNRqRtNtVj902-gnVLeCCGUKEYUWUcbvDWMC6030eQ2xSYMQ42Ar-OY3cwVX3uX8RUMqZ-PwePjCENw-9hF_BRrqa7H9xkKxNGNIUWcpvgBZpABP4fRDSHik4YyfAbT4ANEP99Ga1PXF9j5qVvo6eL88fSqubm7vD49vmk8E3xsRDdppaRaKd855rVm2mvBjVagNRXaecMkmyguOPetNx0FLY1SUnXMiMV8Cx0tfd9rN8DEw9dDvX3PYXB5bpML9v8mhlf7kmbWcEGkIguDvR-DnD4qlNG-pZrjIrNlimgppDJmodpfqnxOpWSY_l6gxH5hsUss9hsL_wRAQX_P</recordid><startdate>20220702</startdate><enddate>20220702</enddate><creator>Abdalla, ELMustafa</creator><creator>Al-Sadi, Anas</creator><creator>Fadul, Abdalla</creator><creator>Ahmed, Ahmed H</creator><creator>Musa, Muzamil</creator><general>Cureus Inc</general><general>Cureus</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20220702</creationdate><title>Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency</title><author>Abdalla, ELMustafa ; Al-Sadi, Anas ; Fadul, Abdalla ; Ahmed, Ahmed H ; Musa, Muzamil</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c243t-4bd5661877cba2c8828c843987e88148ac9262d73433c5c9b1e8697767b294d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Abdomen</topic><topic>Anemia</topic><topic>Asymptomatic</topic><topic>Blood</topic><topic>Case reports</topic><topic>Cell division</topic><topic>Dehydrogenases</topic><topic>Dyspnea</topic><topic>Hematology</topic><topic>Hemoglobin</topic><topic>Immunology</topic><topic>Internal Medicine</topic><topic>Neurology</topic><topic>Pain</topic><topic>Thyroid gland</topic><topic>Veganism</topic><topic>Vitamin B</topic><topic>Vitamin deficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abdalla, ELMustafa</creatorcontrib><creatorcontrib>Al-Sadi, Anas</creatorcontrib><creatorcontrib>Fadul, Abdalla</creatorcontrib><creatorcontrib>Ahmed, Ahmed H</creatorcontrib><creatorcontrib>Musa, Muzamil</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Access via ProQuest (Open Access)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abdalla, ELMustafa</au><au>Al-Sadi, Anas</au><au>Fadul, Abdalla</au><au>Ahmed, Ahmed H</au><au>Musa, Muzamil</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><date>2022-07-02</date><risdate>2022</risdate><volume>14</volume><issue>7</issue><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>Vitamin B12 deficiency is a multifactorial condition, with a wide range of clinical presentations from mild to severe anemia and anemia-related neurological deficits. Hemolysis is a unique cause but has increasingly been recognized lately as a possible B12 deficiency presentation. Our patient presented with hemolytic anemia, for which extensive workup has excluded the common hemolysis etiologies. Therefore, it was attributed to B12 deficiency and improved significantly after treatment. Our case highlights the significance of this unusual presentation and its clinical implementation.</abstract><cop>Palo Alto</cop><pub>Cureus Inc</pub><pmid>35923488</pmid><doi>10.7759/cureus.26507</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2168-8184 |
| ispartof | Curēus (Palo Alto, CA), 2022-07, Vol.14 (7) |
| issn | 2168-8184 2168-8184 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9340670 |
| source | PubMed Central Open Access; PubMed Central |
| subjects | Abdomen Anemia Asymptomatic Blood Case reports Cell division Dehydrogenases Dyspnea Hematology Hemoglobin Immunology Internal Medicine Neurology Pain Thyroid gland Veganism Vitamin B Vitamin deficiency |
| title | Non-immune Intravascular Hemolytic Anemia, an Unusual Presentation of Severe Vitamin B-12 Deficiency |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-18T02%3A14%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Non-immune%20Intravascular%20Hemolytic%20Anemia,%20an%20Unusual%20Presentation%20of%20Severe%20Vitamin%20B-12%20Deficiency&rft.jtitle=Cur%C4%93us%20(Palo%20Alto,%20CA)&rft.au=Abdalla,%20ELMustafa&rft.date=2022-07-02&rft.volume=14&rft.issue=7&rft.issn=2168-8184&rft.eissn=2168-8184&rft_id=info:doi/10.7759/cureus.26507&rft_dat=%3Cproquest_pubme%3E2708646799%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2708646799&rft_id=info:pmid/35923488&rfr_iscdi=true |