Development and characterization of human fetal female reproductive tract organoids to understand Müllerian duct anomalies

Müllerian ducts are paired tubular structures that give rise to most of the female reproductive organs. Any abnormalities in the development and differentiation of these ducts lead to anatomical defects in the female reproductive tract organs categorized as Müllerian duct anomalies. Due to the limit...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2022-07, Vol.119 (30), p.e2118054119-e2118054119
Hauptverfasser:	Venkata, Varshini D, Jamaluddin, M Fairuz B, Goad, Jyoti, Drury, Hannah R, Tadros, Melissa A, Lim, Rebecca, Karakoti, Ajay, O'Sullivan, Rachel, Ius, Yvette, Jaaback, Kenneth, Nahar, Pravin, Tanwar, Pradeep S
Format:	Artikel
Sprache:	eng
Schlagworte:	Abnormalities Adult Animals Anomalies Biological Sciences Defects Ducts Epithelium Fallopian tube Fallopian tubes Fallopian Tubes - growth & development Female Females Fetus Fetuses Human performance Humans Ligands Mice Muellerian duct Mullerian Ducts - abnormalities Organoids Organoids - growth & development Organoids - metabolism Organs Reproductive organs Reproductive system Scaffolds Supplements Transplantation Tubes Uterus Uterus - growth & development Wnt protein Wnt Signaling Pathway
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