Retention of functional mitochondria in mature RBCs from patients with SCD

Sickle cell disease (SCD) is an inherited blood disorder characterized by sickled red blood cells (RBCs), which are more sensitive to hemolysis and can contribute to disease pathophysiology. Although treatment of SCD can include RBC transfusion, patients with SCD have high rates of alloimmunization....

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Veröffentlicht in:British journal of haematology 2022-06, Vol.198 (3), p.574-586
Hauptverfasser: Moriconi, Chiara, Dzieciaktowska, Monika, Roy, Micaela, D’Alessandro, Angelo, Roingeard, Philippe, Lee, June Young, Gibb, David R., Tredicine, Maria, McGill, Marlon A., Qiu, Annie, La Carpia, Francesca, Francis, Richard O., Hod, Eldad A., Thomas, Tiffany, Picard, Martin, Akpan, Imo J., Luckey, Chance John, Zimring, James C., Spitalnik, Steven L., Hudson, Krystalyn E.
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Sprache:eng
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