Extract from Mulberry (Morus australis) leaf decelerate acetaminophen induced hepatic inflammation involving downregulation of myeloid differentiation factor 88 (MyD88) signals

Acetaminophen (APAP) induced inflammation and oxidative stress can cause cell death to induce liver damage. The antioxidative and anti-inflammatory effect of Mulberry (Morus australis) leaf extract (MLE) was shown in previous studies. In this study, we investigated the modulation of MLE on APAP indu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Yàowu shi͡p︡in fenxi 2017-10, Vol.25 (4), p.862-871
Hauptverfasser:	Horng, Chi-Ting, Liu, Zhi-Hong, Huang, Yu-Ting, Lee, Huei-Jane, Wang, Chau-Jong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen Acetaminophen - adverse effects Acids Analgesics Animals antiinflammation antioxidation Apoptosis Atherosclerosis c-Jun protein Catalase Cell death Chemical and Drug Induced Liver Injury - drug therapy Chemical and Drug Induced Liver Injury - etiology Chemical and Drug Induced Liver Injury - genetics Chemical and Drug Induced Liver Injury - immunology Chemokines Chromatography Constituents Cyclooxygenase-2 Cytochrome Cytokines Deceleration Diet Differentiation Down-Regulation Gallic acid Glutathione Glutathione peroxidase Hepatocytes Humans Immunity Infiltration Inflammation JNK protein Kinases Laboratory animals Leaves Liver Liver - drug effects Liver - immunology Liver cancer Male Morus - chemistry Morus australis mulberry leaf MyD88 protein Myeloid Differentiation Factor 88 - genetics Myeloid Differentiation Factor 88 - immunology NF-κB protein Nitric oxide Nitric-oxide synthase Original Oxidative Stress Peroxidase Plant Extracts - administration & dosage Plant Extracts - isolation & purification Plant Leaves - chemistry Polyphenols Pretreatment Protein expression Proteins Protocatechuic acid Rats, Wistar Rodents Superoxide dismutase Transcription factors Tumor necrosis factor-TNF
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!