Validated single urinary assay designed for exposomic multi-class biomarkers of common environmental exposures

Epidemiological studies often call for analytical methods that use a small biospecimen volume to quantify trace level exposures to environmental chemical mixtures. Currently, as many as 150 polar metabolites of environmental chemicals have been found in urine. Therefore, we developed a multi-class m...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2022-08, Vol.414 (19), p.5943-5966
Hauptverfasser:	Jagani, Ravikumar, Pulivarthi, Divya, Patel, Dhavalkumar, Wright, Rosalind J., Wright, Robert O., Arora, Manish, Wolff, Mary S., Andra, Syam S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical Chemistry Assaying Biochemistry Biological markers Biomarkers Biomarkers - urine Characterization and Evaluation of Materials Chemicals Chemistry Chemistry and Materials Science Drug abuse Environmental Exposure - analysis Epidemiology Exposure Extraction (Chemistry) Flame retardants Flame Retardants - analysis Food Science GLP-1 receptor agonists High performance liquid chromatography Humans Laboratory Medicine Liquid chromatography Mass spectrometry Mass spectroscopy Metabolites Methods Monitoring/Environmental Analysis Organic compounds Organophosphates Pesticides Pesticides - analysis Polycyclic aromatic hydrocarbons Population studies Quantitation Research Paper Sample preparation Solid phases Tandem Mass Spectrometry - methods Tobacco Urine VOCs Volatile hydrocarbons Volatile organic compounds
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