B‐flow/spatiotemporal image correlation M‐mode: novel ultrasound method that detects decrease in spiral artery luminal diameter in first trimester in primate model of impaired spiral artery remodeling
ABSTRACT Objective To determine if B‐flow/spatiotemporal image correlation (STIC) M‐mode ultrasonography detects a decrease in spiral artery luminal diameter and volume flow during the first trimester in a non‐human primate model of impaired spiral artery remodeling (SAR). Methods Pregnant baboons w...
Gespeichert in:
| Veröffentlicht in: | Ultrasound in obstetrics & gynecology 2022-03, Vol.59 (3), p.358-364 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 364 |
|---|---|
| container_issue | 3 |
| container_start_page | 358 |
| container_title | Ultrasound in obstetrics & gynecology |
| container_volume | 59 |
| creator | Turan, O. M. Babischkin, J. S. Aberdeen, G. W. Turan, S. Harman, C. R. Pepe, G. J. Albrecht, E. D. |
| description | ABSTRACT
Objective
To determine if B‐flow/spatiotemporal image correlation (STIC) M‐mode ultrasonography detects a decrease in spiral artery luminal diameter and volume flow during the first trimester in a non‐human primate model of impaired spiral artery remodeling (SAR).
Methods
Pregnant baboons were treated daily with estradiol benzoate on days 25–59 of the first trimester (term, 184 days), or remained untreated. On day 60 of gestation, spiral artery luminal diameter (in seven untreated and 12 estradiol‐treated baboons) and volume flow (in four untreated and eight estradiol‐treated baboons) were quantified by B‐flow/STIC M‐mode ultrasonography. In addition, in 15 untreated and 18 estradiol‐treated baboons, the percent of spiral arteries remodeled by extravillous trophoblasts was quantified ex vivo by immunohistochemical image analysis on placental basal plate tissue collected via Cesarean section on day 60. Findings were compared between treated and untreated animals. The correlation between spiral artery luminal diameter and percent of SAR was assessed in three untreated and six estradiol‐treated baboons which underwent both B‐flow/STIC M‐mode ultrasound and quantification of SAR.
Results
The proportion of spiral arteries greater than 50 µm in diameter remodeled by extravillous trophoblasts was 70% lower in estradiol‐treated baboons than in untreated animals (P = 0.000001). Spiral artery luminal diameter in systole and diastole, as quantified by B‐flow/STIC M‐mode in the first trimester of pregnancy, was 31% (P = 0.014) and 50% (P = 0.005) lower, respectively, and volume flow was 85% lower (P = 0.014), in SAR‐suppressed baboons compared with untreated animals. There was a significant correlation between spiral artery luminal diameter as quantified by B‐flow/STIC M‐mode ultrasonography and the percent of SAR (P |
| doi_str_mv | 10.1002/uog.23753 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9301675</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2559429763</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4433-b28ae32921fa05722f343c9ef4c0c2f7343dc771e4b9c411bc1f3b9d21a2754e3</originalsourceid><addsrcrecordid>eNp1ks1u1DAUhS0EosPAghdAltjAIh3_JalZIEEFBamoG7q2HOdmxpUTB9tpNbs-Qh-Mp-BJcGaGCiqxsq7v5-Pj64PQS0qOKSFsNfn1MeN1yR-hBRWVLEhNysdoQWRFirqS7Ag9i_GKEFIJXj1FR1zw8oTXdIF-fvx1e9c5f7OKo07WJ-hHH7TDttdrwMaHAG5uDPhbJnvfwjs8-GtweHIp6OinocU9pI1vcdrohFtIYFLMqwmgI2A74DjaWVOHBGGL3dTbIZet1fkghJnobIgJp2B7iIetMRc6AZ7vdNh32dKobYD2gVyAHWGH9XP0pNMuwovDukSXnz99P_1SnF-cfT39cF4YITgvGnaigTPJaKdJWTPW5XkYCZ0wxLCuzlVr6pqCaKQRlDaGdryRLaOa1aUAvkTv97rj1PTQGhjyJJzaGQ5b5bVV_3YGu1Frf60kJ7TK_7REbw4Cwf-Y8otVb6MB5_QAfoqKlaUUTNYVz-jrB-iVn0IeX6YqXjLBpaCZerunTPAxBujuzVCi5oyonBG1y0hmX_3t_p78E4oMrPbAjXWw_b-Surw420v-BktxzqE</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2635243941</pqid></control><display><type>article</type><title>B‐flow/spatiotemporal image correlation M‐mode: novel ultrasound method that detects decrease in spiral artery luminal diameter in first trimester in primate model of impaired spiral artery remodeling</title><source>MEDLINE</source><source>Wiley Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Wiley Online Library (Open Access Collection)</source><creator>Turan, O. M. ; Babischkin, J. S. ; Aberdeen, G. W. ; Turan, S. ; Harman, C. R. ; Pepe, G. J. ; Albrecht, E. D.</creator><creatorcontrib>Turan, O. M. ; Babischkin, J. S. ; Aberdeen, G. W. ; Turan, S. ; Harman, C. R. ; Pepe, G. J. ; Albrecht, E. D.</creatorcontrib><description>ABSTRACT
Objective
To determine if B‐flow/spatiotemporal image correlation (STIC) M‐mode ultrasonography detects a decrease in spiral artery luminal diameter and volume flow during the first trimester in a non‐human primate model of impaired spiral artery remodeling (SAR).
Methods
Pregnant baboons were treated daily with estradiol benzoate on days 25–59 of the first trimester (term, 184 days), or remained untreated. On day 60 of gestation, spiral artery luminal diameter (in seven untreated and 12 estradiol‐treated baboons) and volume flow (in four untreated and eight estradiol‐treated baboons) were quantified by B‐flow/STIC M‐mode ultrasonography. In addition, in 15 untreated and 18 estradiol‐treated baboons, the percent of spiral arteries remodeled by extravillous trophoblasts was quantified ex vivo by immunohistochemical image analysis on placental basal plate tissue collected via Cesarean section on day 60. Findings were compared between treated and untreated animals. The correlation between spiral artery luminal diameter and percent of SAR was assessed in three untreated and six estradiol‐treated baboons which underwent both B‐flow/STIC M‐mode ultrasound and quantification of SAR.
Results
The proportion of spiral arteries greater than 50 µm in diameter remodeled by extravillous trophoblasts was 70% lower in estradiol‐treated baboons than in untreated animals (P = 0.000001). Spiral artery luminal diameter in systole and diastole, as quantified by B‐flow/STIC M‐mode in the first trimester of pregnancy, was 31% (P = 0.014) and 50% (P = 0.005) lower, respectively, and volume flow was 85% lower (P = 0.014), in SAR‐suppressed baboons compared with untreated animals. There was a significant correlation between spiral artery luminal diameter as quantified by B‐flow/STIC M‐mode ultrasonography and the percent of SAR (P < 0.05).
Conclusion
B‐flow/STIC M‐mode ultrasonography provides a novel real‐time non‐invasive method to detect a decrease in uterine spiral artery luminal diameter and volume flow during the cardiac cycle, reflecting decreased distensibility of the vessel wall, in the first trimester in a non‐human primate model of defective SAR. © 2021 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</description><identifier>ISSN: 0960-7692</identifier><identifier>EISSN: 1469-0705</identifier><identifier>DOI: 10.1002/uog.23753</identifier><identifier>PMID: 34358371</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>17β-Estradiol ; Animals ; Arteries ; Baboons ; Benzoates ; B‐flow ; Cesarean Section ; Correlation ; Diastole ; Estradiol - pharmacology ; Female ; Gynecology ; Humans ; Image analysis ; Image processing ; M‐mode ; Obstetrics ; Original Paper ; Original Papers ; Placenta - diagnostic imaging ; Pregnancy ; Pregnancy Trimester, First ; primate ; Primates ; remodeling ; Sex hormones ; spiral artery diameter ; STIC ; Systole ; Trophoblasts ; Ultrasonic imaging ; Ultrasonic methods ; Ultrasonic testing ; Ultrasonography ; Ultrasound ; uterine ; Uterine Artery - diagnostic imaging ; Uterus ; Veins & arteries</subject><ispartof>Ultrasound in obstetrics & gynecology, 2022-03, Vol.59 (3), p.358-364</ispartof><rights>2021 The Authors. published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</rights><rights>2021 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</rights><rights>2021. This article is published under http://creativecommons.org/licenses/by-nc-nd/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4433-b28ae32921fa05722f343c9ef4c0c2f7343dc771e4b9c411bc1f3b9d21a2754e3</citedby><cites>FETCH-LOGICAL-c4433-b28ae32921fa05722f343c9ef4c0c2f7343dc771e4b9c411bc1f3b9d21a2754e3</cites><orcidid>0000-0003-2827-9739</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fuog.23753$$EPDF$$P50$$Gwiley$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fuog.23753$$EHTML$$P50$$Gwiley$$Hfree_for_read</linktohtml><link.rule.ids>230,314,780,784,885,1417,1433,27924,27925,45574,45575,46409,46833</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/34358371$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Turan, O. M.</creatorcontrib><creatorcontrib>Babischkin, J. S.</creatorcontrib><creatorcontrib>Aberdeen, G. W.</creatorcontrib><creatorcontrib>Turan, S.</creatorcontrib><creatorcontrib>Harman, C. R.</creatorcontrib><creatorcontrib>Pepe, G. J.</creatorcontrib><creatorcontrib>Albrecht, E. D.</creatorcontrib><title>B‐flow/spatiotemporal image correlation M‐mode: novel ultrasound method that detects decrease in spiral artery luminal diameter in first trimester in primate model of impaired spiral artery remodeling</title><title>Ultrasound in obstetrics & gynecology</title><addtitle>Ultrasound Obstet Gynecol</addtitle><description>ABSTRACT
Objective
To determine if B‐flow/spatiotemporal image correlation (STIC) M‐mode ultrasonography detects a decrease in spiral artery luminal diameter and volume flow during the first trimester in a non‐human primate model of impaired spiral artery remodeling (SAR).
Methods
Pregnant baboons were treated daily with estradiol benzoate on days 25–59 of the first trimester (term, 184 days), or remained untreated. On day 60 of gestation, spiral artery luminal diameter (in seven untreated and 12 estradiol‐treated baboons) and volume flow (in four untreated and eight estradiol‐treated baboons) were quantified by B‐flow/STIC M‐mode ultrasonography. In addition, in 15 untreated and 18 estradiol‐treated baboons, the percent of spiral arteries remodeled by extravillous trophoblasts was quantified ex vivo by immunohistochemical image analysis on placental basal plate tissue collected via Cesarean section on day 60. Findings were compared between treated and untreated animals. The correlation between spiral artery luminal diameter and percent of SAR was assessed in three untreated and six estradiol‐treated baboons which underwent both B‐flow/STIC M‐mode ultrasound and quantification of SAR.
Results
The proportion of spiral arteries greater than 50 µm in diameter remodeled by extravillous trophoblasts was 70% lower in estradiol‐treated baboons than in untreated animals (P = 0.000001). Spiral artery luminal diameter in systole and diastole, as quantified by B‐flow/STIC M‐mode in the first trimester of pregnancy, was 31% (P = 0.014) and 50% (P = 0.005) lower, respectively, and volume flow was 85% lower (P = 0.014), in SAR‐suppressed baboons compared with untreated animals. There was a significant correlation between spiral artery luminal diameter as quantified by B‐flow/STIC M‐mode ultrasonography and the percent of SAR (P < 0.05).
Conclusion
B‐flow/STIC M‐mode ultrasonography provides a novel real‐time non‐invasive method to detect a decrease in uterine spiral artery luminal diameter and volume flow during the cardiac cycle, reflecting decreased distensibility of the vessel wall, in the first trimester in a non‐human primate model of defective SAR. © 2021 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</description><subject>17β-Estradiol</subject><subject>Animals</subject><subject>Arteries</subject><subject>Baboons</subject><subject>Benzoates</subject><subject>B‐flow</subject><subject>Cesarean Section</subject><subject>Correlation</subject><subject>Diastole</subject><subject>Estradiol - pharmacology</subject><subject>Female</subject><subject>Gynecology</subject><subject>Humans</subject><subject>Image analysis</subject><subject>Image processing</subject><subject>M‐mode</subject><subject>Obstetrics</subject><subject>Original Paper</subject><subject>Original Papers</subject><subject>Placenta - diagnostic imaging</subject><subject>Pregnancy</subject><subject>Pregnancy Trimester, First</subject><subject>primate</subject><subject>Primates</subject><subject>remodeling</subject><subject>Sex hormones</subject><subject>spiral artery diameter</subject><subject>STIC</subject><subject>Systole</subject><subject>Trophoblasts</subject><subject>Ultrasonic imaging</subject><subject>Ultrasonic methods</subject><subject>Ultrasonic testing</subject><subject>Ultrasonography</subject><subject>Ultrasound</subject><subject>uterine</subject><subject>Uterine Artery - diagnostic imaging</subject><subject>Uterus</subject><subject>Veins & arteries</subject><issn>0960-7692</issn><issn>1469-0705</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>EIF</sourceid><recordid>eNp1ks1u1DAUhS0EosPAghdAltjAIh3_JalZIEEFBamoG7q2HOdmxpUTB9tpNbs-Qh-Mp-BJcGaGCiqxsq7v5-Pj64PQS0qOKSFsNfn1MeN1yR-hBRWVLEhNysdoQWRFirqS7Ag9i_GKEFIJXj1FR1zw8oTXdIF-fvx1e9c5f7OKo07WJ-hHH7TDttdrwMaHAG5uDPhbJnvfwjs8-GtweHIp6OinocU9pI1vcdrohFtIYFLMqwmgI2A74DjaWVOHBGGL3dTbIZet1fkghJnobIgJp2B7iIetMRc6AZ7vdNh32dKobYD2gVyAHWGH9XP0pNMuwovDukSXnz99P_1SnF-cfT39cF4YITgvGnaigTPJaKdJWTPW5XkYCZ0wxLCuzlVr6pqCaKQRlDaGdryRLaOa1aUAvkTv97rj1PTQGhjyJJzaGQ5b5bVV_3YGu1Frf60kJ7TK_7REbw4Cwf-Y8otVb6MB5_QAfoqKlaUUTNYVz-jrB-iVn0IeX6YqXjLBpaCZerunTPAxBujuzVCi5oyonBG1y0hmX_3t_p78E4oMrPbAjXWw_b-Surw420v-BktxzqE</recordid><startdate>202203</startdate><enddate>202203</enddate><creator>Turan, O. M.</creator><creator>Babischkin, J. S.</creator><creator>Aberdeen, G. W.</creator><creator>Turan, S.</creator><creator>Harman, C. R.</creator><creator>Pepe, G. J.</creator><creator>Albrecht, E. D.</creator><general>John Wiley & Sons, Ltd</general><general>Wiley Subscription Services, Inc</general><scope>24P</scope><scope>WIN</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0003-2827-9739</orcidid></search><sort><creationdate>202203</creationdate><title>B‐flow/spatiotemporal image correlation M‐mode: novel ultrasound method that detects decrease in spiral artery luminal diameter in first trimester in primate model of impaired spiral artery remodeling</title><author>Turan, O. M. ; Babischkin, J. S. ; Aberdeen, G. W. ; Turan, S. ; Harman, C. R. ; Pepe, G. J. ; Albrecht, E. D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4433-b28ae32921fa05722f343c9ef4c0c2f7343dc771e4b9c411bc1f3b9d21a2754e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>17β-Estradiol</topic><topic>Animals</topic><topic>Arteries</topic><topic>Baboons</topic><topic>Benzoates</topic><topic>B‐flow</topic><topic>Cesarean Section</topic><topic>Correlation</topic><topic>Diastole</topic><topic>Estradiol - pharmacology</topic><topic>Female</topic><topic>Gynecology</topic><topic>Humans</topic><topic>Image analysis</topic><topic>Image processing</topic><topic>M‐mode</topic><topic>Obstetrics</topic><topic>Original Paper</topic><topic>Original Papers</topic><topic>Placenta - diagnostic imaging</topic><topic>Pregnancy</topic><topic>Pregnancy Trimester, First</topic><topic>primate</topic><topic>Primates</topic><topic>remodeling</topic><topic>Sex hormones</topic><topic>spiral artery diameter</topic><topic>STIC</topic><topic>Systole</topic><topic>Trophoblasts</topic><topic>Ultrasonic imaging</topic><topic>Ultrasonic methods</topic><topic>Ultrasonic testing</topic><topic>Ultrasonography</topic><topic>Ultrasound</topic><topic>uterine</topic><topic>Uterine Artery - diagnostic imaging</topic><topic>Uterus</topic><topic>Veins & arteries</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Turan, O. M.</creatorcontrib><creatorcontrib>Babischkin, J. S.</creatorcontrib><creatorcontrib>Aberdeen, G. W.</creatorcontrib><creatorcontrib>Turan, S.</creatorcontrib><creatorcontrib>Harman, C. R.</creatorcontrib><creatorcontrib>Pepe, G. J.</creatorcontrib><creatorcontrib>Albrecht, E. D.</creatorcontrib><collection>Wiley Online Library (Open Access Collection)</collection><collection>Wiley Online Library (Open Access Collection)</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Ultrasound in obstetrics & gynecology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Turan, O. M.</au><au>Babischkin, J. S.</au><au>Aberdeen, G. W.</au><au>Turan, S.</au><au>Harman, C. R.</au><au>Pepe, G. J.</au><au>Albrecht, E. D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>B‐flow/spatiotemporal image correlation M‐mode: novel ultrasound method that detects decrease in spiral artery luminal diameter in first trimester in primate model of impaired spiral artery remodeling</atitle><jtitle>Ultrasound in obstetrics & gynecology</jtitle><addtitle>Ultrasound Obstet Gynecol</addtitle><date>2022-03</date><risdate>2022</risdate><volume>59</volume><issue>3</issue><spage>358</spage><epage>364</epage><pages>358-364</pages><issn>0960-7692</issn><eissn>1469-0705</eissn><abstract>ABSTRACT
Objective
To determine if B‐flow/spatiotemporal image correlation (STIC) M‐mode ultrasonography detects a decrease in spiral artery luminal diameter and volume flow during the first trimester in a non‐human primate model of impaired spiral artery remodeling (SAR).
Methods
Pregnant baboons were treated daily with estradiol benzoate on days 25–59 of the first trimester (term, 184 days), or remained untreated. On day 60 of gestation, spiral artery luminal diameter (in seven untreated and 12 estradiol‐treated baboons) and volume flow (in four untreated and eight estradiol‐treated baboons) were quantified by B‐flow/STIC M‐mode ultrasonography. In addition, in 15 untreated and 18 estradiol‐treated baboons, the percent of spiral arteries remodeled by extravillous trophoblasts was quantified ex vivo by immunohistochemical image analysis on placental basal plate tissue collected via Cesarean section on day 60. Findings were compared between treated and untreated animals. The correlation between spiral artery luminal diameter and percent of SAR was assessed in three untreated and six estradiol‐treated baboons which underwent both B‐flow/STIC M‐mode ultrasound and quantification of SAR.
Results
The proportion of spiral arteries greater than 50 µm in diameter remodeled by extravillous trophoblasts was 70% lower in estradiol‐treated baboons than in untreated animals (P = 0.000001). Spiral artery luminal diameter in systole and diastole, as quantified by B‐flow/STIC M‐mode in the first trimester of pregnancy, was 31% (P = 0.014) and 50% (P = 0.005) lower, respectively, and volume flow was 85% lower (P = 0.014), in SAR‐suppressed baboons compared with untreated animals. There was a significant correlation between spiral artery luminal diameter as quantified by B‐flow/STIC M‐mode ultrasonography and the percent of SAR (P < 0.05).
Conclusion
B‐flow/STIC M‐mode ultrasonography provides a novel real‐time non‐invasive method to detect a decrease in uterine spiral artery luminal diameter and volume flow during the cardiac cycle, reflecting decreased distensibility of the vessel wall, in the first trimester in a non‐human primate model of defective SAR. © 2021 The Authors. Ultrasound in Obstetrics & Gynecology published by John Wiley & Sons Ltd on behalf of International Society of Ultrasound in Obstetrics and Gynecology.</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>34358371</pmid><doi>10.1002/uog.23753</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-2827-9739</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0960-7692 |
| ispartof | Ultrasound in obstetrics & gynecology, 2022-03, Vol.59 (3), p.358-364 |
| issn | 0960-7692 1469-0705 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9301675 |
| source | MEDLINE; Wiley Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wiley Online Library (Open Access Collection) |
| subjects | 17β-Estradiol Animals Arteries Baboons Benzoates B‐flow Cesarean Section Correlation Diastole Estradiol - pharmacology Female Gynecology Humans Image analysis Image processing M‐mode Obstetrics Original Paper Original Papers Placenta - diagnostic imaging Pregnancy Pregnancy Trimester, First primate Primates remodeling Sex hormones spiral artery diameter STIC Systole Trophoblasts Ultrasonic imaging Ultrasonic methods Ultrasonic testing Ultrasonography Ultrasound uterine Uterine Artery - diagnostic imaging Uterus Veins & arteries |
| title | B‐flow/spatiotemporal image correlation M‐mode: novel ultrasound method that detects decrease in spiral artery luminal diameter in first trimester in primate model of impaired spiral artery remodeling |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T07%3A27%3A26IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=B%E2%80%90flow/spatiotemporal%20image%20correlation%20M%E2%80%90mode:%20novel%20ultrasound%20method%20that%20detects%20decrease%20in%20spiral%20artery%20luminal%20diameter%20in%20first%20trimester%20in%20primate%20model%20of%20impaired%20spiral%20artery%20remodeling&rft.jtitle=Ultrasound%20in%20obstetrics%20&%20gynecology&rft.au=Turan,%20O.%20M.&rft.date=2022-03&rft.volume=59&rft.issue=3&rft.spage=358&rft.epage=364&rft.pages=358-364&rft.issn=0960-7692&rft.eissn=1469-0705&rft_id=info:doi/10.1002/uog.23753&rft_dat=%3Cproquest_pubme%3E2559429763%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2635243941&rft_id=info:pmid/34358371&rfr_iscdi=true |