Structure of Reelin repeat 8 and the adjacent C-terminal region

Neuronal development and function are dependent in part on the several roles of the secreted glycoprotein Reelin. Endogenous proteases process this 400 kDa, modular protein, yielding N-terminal, central, and C-terminal fragments that each have distinct roles in Reelin’s function and regulation. The...

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Veröffentlicht in:	Biophysical journal 2022-07, Vol.121 (13), p.2526-2537
Hauptverfasser:	Turk, Liam S., Currie, Michael J., Dobson, Renwick C.J., Comoletti, Davide
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Adhesion Molecules, Neuronal - chemistry Extracellular Matrix Proteins - genetics Nerve Tissue Proteins - chemistry Neurons - metabolism Reelin Protein Serine Endopeptidases - chemistry Serine Endopeptidases - genetics Serine Endopeptidases - metabolism
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