Oxygenated versus non‐oxygenated flush out and storage of donor livers: An experimental study

Background During donor organ procurement and subsequent static cold storage (SCS), hepatic adenosine triphosphate (ATP) levels are progressively depleted, which contributes to ischemia‐reperfusion injury (IRI). We sought to investigate a simple approach to prevent ATP depletion and IRI using a porc...

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Veröffentlicht in:	Artificial organs 2022-02, Vol.46 (2), p.201-209
Hauptverfasser:	Brüggenwirth, Isabel M. A., Plas, Willemijn S., Leeuwen, Otto B., Thorne, Adam M., Rayar, Michel, Meijer, Vincent E., Porte, Robert J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine triphosphate Adenosine Triphosphate - metabolism Animals ATP Bicarbonates Bile - chemistry Bile ducts Blood Cold storage Cryopreservation Deoxyribonucleic acid Depletion DNA Female Flavin mononucleotide Glucose Injury prevention Ischemia ischemia‐reperfusion injury L-Lactate dehydrogenase Lactate dehydrogenase Lactic acid Liver Liver - chemistry Liver - physiopathology Liver Transplantation Liver transplants Main Text Malondialdehyde organ preservation Organ Preservation - methods Organ Preservation Solutions Oxygen - pharmacology Oxygenation Parenchyma Portal vein Reperfusion Reperfusion Injury - metabolism Reperfusion Injury - prevention & control static cold storage Sus scrofa
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