Metabolic Labeling of Legionaminic Acid in Flagellin Glycosylation of Campylobacter jejuni Identifies Maf4 as a Putative Legionaminyl Transferase

Campylobacter jejuni is the major human food‐borne pathogen. Its bipolar flagella are heavily O‐glycosylated with microbial sialic acids and essential for its motility and pathogenicity. However, both the glycosylation of flagella and the exact contribution of legionaminic acid (Leg) to flagellar ac...

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Veröffentlicht in:	Angewandte Chemie International Edition 2021-11, Vol.60 (47), p.24811-24816
Hauptverfasser:	Meng, Xianke, Boons, Geert‐Jan, Wösten, Marc M. S. M., Wennekes, Tom
Format:	Artikel
Sprache:	eng
Schlagworte:	bacterial flagella Campylobacter Campylobacter jejuni Campylobacter jejuni - chemistry Campylobacter jejuni - metabolism Carbohydrate Conformation carbohydrates Communication Communications Flagella Flagellin Flagellin - chemistry Flagellin - metabolism glycoproteins Glycosylation Glycosyltransferase Humans Invasiveness Labeling Leg Legionaminic acid metabolic labeling Metabolism Microorganisms Motility Pathogenicity Pathogens Probes Sialic acids Sialic Acids - analysis Sialic Acids - metabolism Transferases - chemistry Transferases - metabolism
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