The use of variable delay multipulse chemical exchange saturation transfer for separately assessing different CEST pools in the human brain at 7T

Purpose Current challenges of in vivo CEST imaging include overlapping signals from different pools. The overlap arises from closely resonating pools and/or the broad magnetization transfer contrast (MTC) from macromolecules. This study aimed to evaluate the feasibility of variable delay multipulse...

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Veröffentlicht in:	Magnetic resonance in medicine 2022-02, Vol.87 (2), p.872-883
Hauptverfasser:	Schmitz‐Abecassis, Bárbara, Vinogradov, Elena, Wijnen, Jannie P., Harten, Thijs, Wiegers, Evita C., Hoogduin, Hans, Osch, Matthias J. P., Ercan, Ece
Format:	Artikel
Sprache:	eng
Schlagworte:	Amides Amines Bovine serum albumin Brain Brain - diagnostic imaging chemical exchange saturation transfer (CEST) Data acquisition Evaluation Foreign exchange rates Humans In vivo methods and tests Macromolecules Magnetic Resonance Imaging Neuroimaging Overhauser effect Phantoms, Imaging Pools Saturation Serum albumin s—Biophysics and Basic Biomedical Research ultrahigh field variable delay multipulse (VDMP)‐CEST
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