A multidisciplinary review about Encephalitozoon cuniculi in a One Health perspective

Encephalitozoon cuniculi is a microsporidian parasite mostly associated with its natural host, the rabbit ( Oryctolagus cuniculus ). However, other animals can be infected, like other mammals, birds, and even humans. Although it usually causes subclinical infection, it can also lead to encephalitozo...

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Veröffentlicht in:Parasitology research (1987) 2022-09, Vol.121 (9), p.2463-2479
Hauptverfasser: Magalhães, Tomás Rodrigues, Pinto, Filipe Fontes, Queiroga, Felisbina Luisa
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container_issue 9
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container_title Parasitology research (1987)
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creator Magalhães, Tomás Rodrigues
Pinto, Filipe Fontes
Queiroga, Felisbina Luisa
description Encephalitozoon cuniculi is a microsporidian parasite mostly associated with its natural host, the rabbit ( Oryctolagus cuniculus ). However, other animals can be infected, like other mammals, birds, and even humans. Although it usually causes subclinical infection, it can also lead to encephalitozoonosis, a clinical disease characterized by neurological, ocular, and/or renal signs that can be even fatal, especially in immunocompromised individuals. Therefore, this multidisciplinary review contributes with updated information about the E. cuniculi , deepening in its molecular and genetic characterization, its mechanisms of infection and transmission, and its prevalence among different species and geographic locations, in a One Health perspective. Recent information about the diagnostic and therapeutic approach in the main host species and the prophylaxis and infection control measures currently suggested are also discussed.
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subjects Biomedical and Life Sciences
Biomedicine
Disease transmission
Encephalitozoon cuniculi
Encephalitozoonosis
Genetic aspects
Immunology
Infection
Medical Microbiology
Microbiology
Prophylaxis
Review
Subclinical infection
title A multidisciplinary review about Encephalitozoon cuniculi in a One Health perspective
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