The evolution of synaptic and cognitive capacity: Insights from the nervous system transcriptome of Aplysia

The gastropod mollusk is an important model for cellular and molecular neurobiological studies, particularly for investigations of molecular mechanisms of learning and memory. We developed an optimized assembly pipeline to generate an improved nervous system transcriptome. This improved transcriptom...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2022-07, Vol.119 (28), p.e2122301119-e2122301119
Hauptverfasser:	Orvis, Joshua, Albertin, Caroline B, Shrestha, Pragya, Chen, Shuangshuang, Zheng, Melanie, Rodriguez, Cheyenne J, Tallon, Luke J, Mahurkar, Anup, Zimin, Aleksey V, Kim, Michelle, Liu, Kelvin, Kandel, Eric R, Fraser, Claire M, Sossin, Wayne, Abrams, Thomas W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aplysia Aplysia - genetics Aplysia - metabolism Biological Evolution Biological Sciences Circuits Cognition Cognitive ability Evolution Genes Genomes Invertebrates Isoforms Molecular modelling Mollusks Nervous system Neuronal Plasticity - genetics Neurons Neurons - metabolism Octopuses Plasticity Protein families Protein Isoforms - genetics Proteins Proteome Proteomes Scaffolds Synapses - metabolism Synaptic plasticity Transcriptome Transcriptomes Vertebrates
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