Septins guide noncentrosomal microtubules to promote focal adhesion disassembly in migrating cells

Endothelial cell migration is critical for vascular angiogenesis and is compromised to facilitate tumor metastasis. The migratory process requires the coordinated assembly and disassembly of focal adhesions (FA), actin, and microtubules (MT). MT dynamics at FAs deliver vesicular cargoes and enhance...

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Veröffentlicht in:	Molecular biology of the cell 2022-05, Vol.33 (5), p.ar40-ar40
Hauptverfasser:	Merenich, Daniel, Nakos, Konstantinos, Pompan, Taylor, Donovan, Samantha J, Gill, Amrik, Patel, Pranav, Spiliotis, Elias T, Myers, Kenneth A
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin Cytoskeleton - metabolism Actins - metabolism Cell Movement - physiology Focal Adhesions - metabolism Microtubules - metabolism Septins - metabolism
Online-Zugang:	Volltext
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