Establishing an 8‐gene immune prognostic model based on TP53 status for lung adenocarcinoma

Background Lung adenocarcinoma (LUAD) results in a majority of cancer burden worldwide. TP53 is the most commonly mutated in LUAD. This study aimed to reveal the relation between TP53 and tumor microenvironment (TME) for improving LUAD treatment. Methods Differentially expressed genes (DEGs) related...

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Veröffentlicht in:	Journal of clinical laboratory analysis 2022-07, Vol.36 (7), p.e24538-n/a
Hauptverfasser:	Wu, Guodong, Wang, Youyu, Wan, Yanhui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma bioinformatics analysis Cancer therapies CD4 antigen Datasets Gene expression Immune checkpoint Immunological memory Immunosuppressive agents lung adenocarcinoma Lung cancer Lymphocytes T Macrophages Medical prognosis Memory cells Mutation p53 Protein Performance evaluation prognostic genes Regression analysis Risk groups Software Statistical analysis Survival analysis TP53 Tumor microenvironment Tumors
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