CD44 potentiates hepatocellular carcinoma migration and extrahepatic metastases via the AKT/ERK signaling CXCR4 axis

BackgroundCell adhesion molecule cluster of differentiation 44 (CD44) plays a significant role in cancer cell local invasion, intravasation, migration, and the establishment of metastatic lesions. However, little is known about the underlying mechanism of how CD44 regulates hepatocellular carcinoma...

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Veröffentlicht in:Annals of translational medicine 2022-06, Vol.10 (12), p.689-689
Hauptverfasser: Xie, Peiyi, Yan, Jiuliang, Wu, Mengyuan, Li, Hui, Chen, Zheng, Yu, Mincheng, Zhang, Bo, Chen, Lingli, Jin, Lei, Zhou, Binghai, Li, Xiaoqiang, Xiao, Yongsheng, Xu, Yongfeng, Long, Jiang, Zhang, Jubo, Guo, Lei
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Sprache:eng
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