4‐phenylpyridine suppresses UVB‐induced skin inflammation by targeting c‐Src in vitro and in vivo

Acute or repetitive exposure to ultraviolet (UV) cause disruptions to the skin barrier and subsequent inflammatory skin disease. 4‐phenylpyridine (4‐PP) is a constituent of Brassica campestris L. ssp. Pekinensis and its effect on skin inflammation and molecular target remain unclear. The purpose of...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2022-07, Vol.26 (14), p.3891-3901
Hauptverfasser:	Kim, Ju Gyeong, Kang, Ha Yeong, Kim, Min Jeong, Lim, Seokwon, Lee, Chang Joo, Kim, Kyung‐Min, Jung, Sung Keun
Format:	Artikel
Sprache:	eng
Schlagworte:	4‐phenylpyridine Animals Biotechnology Brassica campestris L. ssp. pekinensis COX‐2 c‐Src Enzymes Epidermal growth factor Epidermal growth factor receptors Gene expression Inflammation JNK protein Keratinocytes Kinases Original Pathogens Phosphorylation phytochemicals Pronase Protein kinase C Proteins Proteolysis Signal transduction Skin cancer Skin diseases skin inflammation Src protein Tyrosine Ultraviolet radiation
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