The NHS England 100,000 Genomes Project: feasibility and utility of centralised genome sequencing for children with cancer

Background Whole-genome sequencing (WGS) of cancers is becoming an accepted component of oncological care, and NHS England is currently rolling out WGS for all children with cancer. This approach was piloted during the 100,000 genomes (100 K) project. Here we share the experience of the East of Engl...

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Veröffentlicht in:	British journal of cancer 2022-07, Vol.127 (1), p.137-144
Hauptverfasser:	Trotman, Jamie, Armstrong, Ruth, Firth, Helen, Trayers, Claire, Watkins, James, Allinson, Kieren, Jacques, Thomas S., Nicholson, James C., Burke, G. A. Amos, Behjati, Sam, Murray, Matthew J., Hook, Catherine E., Tarpey, Patrick
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/69 692/4028/67/69 Biomedical and Life Sciences Biomedicine Cancer Cancer Research Child Children Drug Resistance Epidemiology Feasibility Studies Genomes Genomics Germ-Line Mutation Humans Molecular Medicine Neoplasms - genetics Oncology Solid tumors State Medicine Whole Genome Sequencing
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