Fibroblast activation protein identifies Consensus Molecular Subtype 4 in colorectal cancer and allows its detection by 68Ga-FAPI-PET imaging

Background In colorectal cancer (CRC), the consensus molecular subtype 4 (CMS4) is associated with therapy resistance and poor prognosis. Clinical diagnosis of CMS4 is hampered by locoregional and temporal variables influencing CMS classification. Diagnostic tools that comprehensively detect CMS4 ar...

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Veröffentlicht in:	British journal of cancer 2022-07, Vol.127 (1), p.145-155
Hauptverfasser:	Strating, Esther, Wassenaar, Emma, Verhagen, Mathijs, Rauwerdink, Paulien, van Schelven, Susanne, de Hingh, Ignace, Rinkes, Inne Borel, Boerma, Djamila, Witkamp, Arjen, Lacle, Miangela, Fodde, Riccardo, Volckmann, Richard, Koster, Jan, Stedingk, Kris, Giesel, Frederik, de Roos, Remmert, Poot, Alex, Bol, Guus, Lam, Marnix, Elias, Sjoerd, Kranenburg, Onno
Format:	Artikel
Sprache:	eng
Schlagworte:	631/67/2321 692/4028/67/1504/1885 Biomedical and Life Sciences Biomedicine Cancer Research Colorectal cancer Colorectal carcinoma Drug Resistance Epidemiology Fibroblast activation protein Fibroblasts Medical prognosis Metastases Metastasis Molecular Medicine mRNA Oncology Patients Peritoneum Positron emission tomography Tumors
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