Counting Advanced Precancerous Lesions as True Positives When Determining Colorectal Cancer Screening Test Specificity

Abstract The landmark Centers for Medicare & Medicaid Services (CMS) decision memo on blood-based biomarkers to screen for colorectal cancer (CRC) sets thresholds of 74% or higher for sensitivity and 90% or higher for specificity for CRC. This approach does not consider detection of advanced pre...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2022-07, Vol.114 (7), p.1040-1043
Hauptverfasser:	Ladabaum, Uri, Church, Timothy R, Feng, Ziding, Ransohoff, David F, Schoen, Robert E
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biomarkers Brief Communications Cancer Cancer screening Colorectal cancer Colorectal carcinoma Colorectal Neoplasms - diagnosis Colorectal Neoplasms - epidemiology Early Detection of Cancer Government programs Humans Lesions Mass Screening Medical screening Medicare Mortality Precancerous Conditions - diagnosis Sensitivity Sensitivity and Specificity United States - epidemiology
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