Maternal obesity alters immune cell frequencies and responses in umbilical cord blood samples

Background Maternal obesity is one of the several key factors thought to modulate neonatal immune system development. Data from murine studies demonstrate worse outcomes in models of infection, autoimmunity, and allergic sensitization in offspring of obese dams. In humans, children born to obese mot...

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Veröffentlicht in:	Pediatric allergy and immunology 2015-06, Vol.26 (4), p.344-351
Hauptverfasser:	Wilson, Randall M., Marshall, Nicole E., Jeske, Daniel R., Purnell, Jonathan Q., Thornburg, Kent, Messaoudi, Ilhem
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Asthma cytokine dendritic cells Eosinophils - immunology Factor Analysis, Statistical Female Fetal Blood - immunology Flow Cytometry Humans Immune system Immune System - immunology maternal obesity monocytes Monocytes - immunology Mothers Mothers - statistics & numerical data Obesity Obesity - blood Obesity - immunology Pediatrics Pregnancy Pregnancy Complications - blood Pregnancy Complications - immunology T cells T-Lymphocytes - immunology toll-like receptor Toll-Like Receptors - blood Toll-Like Receptors - immunology
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