Cancer-Associated Fibroblast-Derived Exosomal miRNA-320a Promotes Macrophage M2 Polarization In Vitro by Regulating PTEN/PI3Kγ Signaling in Pancreatic Cancer

Our previous study has indicated that cancer-associated fibroblasts (CAFs) play a crucial role in regulating gemcitabine resistance through transferring exosomal miRNA-106b to cancer cells. Tumor-associated macrophages (TAMs) are recently verified to facilitate gemcitabine resistance. However, the e...

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Veröffentlicht in:	Journal of oncology 2022-07, Vol.2022, p.1-11
Hauptverfasser:	Zhao, Mingkun, Zhuang, Aobo, Fang, Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Cancer Cancer therapies Cytotoxicity Fibroblasts Gene expression Growth factors Macrophages MicroRNA MicroRNAs Oncology, Experimental Pancreatic cancer Proteins Public health Tumors
Online-Zugang:	Volltext
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