SAGA-Dependent Histone H2Bub1 Deubiquitination Is Essential for Cellular Ubiquitin Balance during Embryonic Development

Ubiquitin (ub) is a small, highly conserved protein widely expressed in eukaryotic cells. Ubiquitination is a post-translational modification catalyzed by enzymes that activate, conjugate, and ligate ub to proteins. Substrates can be modified either by addition of a single ubiquitin molecule (monoub...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular sciences 2022-07, Vol.23 (13), p.7459
Hauptverfasser:	El-Saafin, Farrah, Devys, Didier, Johnsen, Steven A., Vincent, Stéphane D., Tora, László
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biochemistry, Molecular Biology Biological activity Chromatin Conjugation Development Biology DNA damage Embryogenesis Embryology and Organogenesis Embryos Enzymes Genes Genomes Histone H2B Histones Homeostasis Life Sciences Mammalian cells Mammals Molecular biology Phenotypes Post-translation Proteins Retention Review RNA polymerase Spatial distribution Stem cells Ubiquitin Ubiquitination Yeast
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!