Monocarboxylate transporter 1 is a novel target for breast cancer stem like‐cell inhibition by diallyl trisulfide

Diallyl trisulfide (DATS) is a promising small molecule phytochemical that exhibits in vitro and in vivo activity in multiple preclinical solid tumor models including breast cancer, but the underlying mechanism is not fully understood. We have shown previously that forkhead box Q1 (FoxQ1) transcript...

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Veröffentlicht in:	Molecular carcinogenesis 2022-08, Vol.61 (8), p.752-763
Hauptverfasser:	Kim, Su‐Hyeong, Singh, Shivendra V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehyde dehydrogenase Allyl Compounds - pharmacology Apoptosis Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - genetics Breast Neoplasms - pathology Cell Line, Tumor Cell migration chemoprevention Diallyl trisulfide Female Forkhead protein Forkhead Transcription Factors - genetics Genomes Humans Lactic acid MCT1 Monocarboxylic Acid Transporters - metabolism Proteins Solid tumors Statistical analysis Sulfides - pharmacology Symporters - metabolism
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