The dsRBP Staufen2 governs RNP assembly of neuronal Argonaute proteins

Abstract Mature microRNAs are bound by a member of the Argonaute (Ago1-4) protein family, forming the core of the RNA-induced silencing complex (RISC). Association of RISC with target mRNAs results in ribonucleoprotein (RNP) assembly involved in translational silencing or RNA degradation. Yet, the d...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Nucleic acids research 2022-07, Vol.50 (12), p.7034-7047
Hauptverfasser:	Ehses, Janina, Schlegel, Melina, Schröger, Luise, Schieweck, Rico, Derdak, Sophia, Bilban, Martin, Bauer, Karl, Harner, Max, Kiebler, Michael A
Format:	Artikel
Sprache:	eng
Schlagworte:	Argonaute Proteins - genetics Neurons - metabolism RNA and RNA-protein complexes RNA-Binding Proteins RNA-Induced Silencing Complex - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!