Exosomal miR-224-5p from Colorectal Cancer Cells Promotes Malignant Transformation of Human Normal Colon Epithelial Cells by Promoting Cell Proliferation through Downregulation of CMTM4

Background. Interactions between malignant cells and neighboring normal cells are important for carcinogenesis. In addition, cancer cell-derived exosomes have been shown to promote the malignant transformation of recipient cells, but the mechanisms remain unclear. Methods. The level of miR-224-5p in...

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Veröffentlicht in:Oxidative medicine and cellular longevity 2022, Vol.2022, p.5983629-14
Hauptverfasser: Wu, Feng, Yang, Jiani, Shang, Guoyin, Zhang, Zhijia, Niu, Sijia, Liu, Yang, Liu, Hongru, Jing, Jing, Fang, Yu
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Sprache:eng
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