Synergistic Effect of Conventional Medicinal Herbs against Different Pharmacological Activity
Triticum aestivum (Family: Poaceae), Ocimum sanctum (Family: Lamiaceae), and Tinospora cordifolia (Family: Menispermaceae) are commonly known as wheatgrass, tulsi, and giloy, respectively, which are the plants used as medicines for the treatment of various diseases. All three medicinal plants posses...
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| creator | Ali, Huma Ali, Daoud Almutairi, Bader O. Kumar, Gokhlesh Karga, Gizachew Assefa Masi, Chandran Sundramurthy, Venkatesa Prabhu |
| description | Triticum aestivum (Family: Poaceae), Ocimum sanctum (Family: Lamiaceae), and Tinospora cordifolia (Family: Menispermaceae) are commonly known as wheatgrass, tulsi, and giloy, respectively, which are the plants used as medicines for the treatment of various diseases. All three medicinal plants possess phenolic compounds with other important chemical constituents such as polysaccharides, aliphatic compounds, and alkaloids. The extract of these plants has been prepared and investigated for antioxidant, total phenolic content, total flavonoid content, and antimicrobial study in order to discover potential sources for new pharmaceutical formulations. To determine the antioxidant activity, a free radical scavenging assay for 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydrogen peroxide was performed using ascorbic acid as the standard. The R2 value of the prepared extract was found to be 0.9964 and 0.990 in DPPH and hydrogen peroxide scavenging activity, respectively. The phenolic and flavonoid content was found to be 87.50 μl/ml and 58.00 μl/ml, respectively. The diffusion method was used to screen the antimicrobial activity of the prepared extract sample against various microorganisms. This extract showed better results for antioxidant and antimicrobial activity. |
| doi_str_mv | 10.1155/2022/7337261 |
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All three medicinal plants possess phenolic compounds with other important chemical constituents such as polysaccharides, aliphatic compounds, and alkaloids. The extract of these plants has been prepared and investigated for antioxidant, total phenolic content, total flavonoid content, and antimicrobial study in order to discover potential sources for new pharmaceutical formulations. To determine the antioxidant activity, a free radical scavenging assay for 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydrogen peroxide was performed using ascorbic acid as the standard. The R2 value of the prepared extract was found to be 0.9964 and 0.990 in DPPH and hydrogen peroxide scavenging activity, respectively. The phenolic and flavonoid content was found to be 87.50 μl/ml and 58.00 μl/ml, respectively. The diffusion method was used to screen the antimicrobial activity of the prepared extract sample against various microorganisms. This extract showed better results for antioxidant and antimicrobial activity.</description><identifier>ISSN: 2314-6133</identifier><identifier>EISSN: 2314-6141</identifier><identifier>DOI: 10.1155/2022/7337261</identifier><identifier>PMID: 35813228</identifier><language>eng</language><publisher>United States: Hindawi</publisher><subject>Aliphatic compounds ; Anesthesia ; Anti-infective agents ; Anti-Infective Agents - pharmacology ; Antiinfectives and antibacterials ; Antimicrobial activity ; Antioxidants ; Antioxidants - chemistry ; Antioxidants - pharmacology ; Ascorbic acid ; Bacteria ; Cancer therapies ; Chemical compounds ; Enzymes ; Ethanol ; Flavonoids ; Flavonoids - pharmacology ; Formulations ; Free radicals ; Health aspects ; Herbal medicine ; Hydrogen Peroxide ; Infections ; Materia medica, Vegetable ; Medicinal herbs ; Medicinal plants ; Medicine ; Metabolism ; Metabolites ; Microorganisms ; Ocimum sanctum ; Pathogens ; Phenolic compounds ; Phenols ; Phenols - pharmacology ; Plant extracts ; Plant Extracts - chemistry ; Plant Extracts - pharmacology ; Plants, Medicinal - chemistry ; Polysaccharides ; Saccharides ; Scavenging ; Synergistic effect ; Testing ; Tinospora cordifolia ; Triticum aestivum ; Viral infections ; Wheat</subject><ispartof>BioMed research international, 2022-06, Vol.2022, p.7337261-7</ispartof><rights>Copyright © 2022 Huma Ali et al.</rights><rights>COPYRIGHT 2022 John Wiley & Sons, Inc.</rights><rights>Copyright © 2022 Huma Ali et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. 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All three medicinal plants possess phenolic compounds with other important chemical constituents such as polysaccharides, aliphatic compounds, and alkaloids. The extract of these plants has been prepared and investigated for antioxidant, total phenolic content, total flavonoid content, and antimicrobial study in order to discover potential sources for new pharmaceutical formulations. To determine the antioxidant activity, a free radical scavenging assay for 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydrogen peroxide was performed using ascorbic acid as the standard. The R2 value of the prepared extract was found to be 0.9964 and 0.990 in DPPH and hydrogen peroxide scavenging activity, respectively. The phenolic and flavonoid content was found to be 87.50 μl/ml and 58.00 μl/ml, respectively. The diffusion method was used to screen the antimicrobial activity of the prepared extract sample against various microorganisms. This extract showed better results for antioxidant and antimicrobial activity.</description><subject>Aliphatic compounds</subject><subject>Anesthesia</subject><subject>Anti-infective agents</subject><subject>Anti-Infective Agents - pharmacology</subject><subject>Antiinfectives and antibacterials</subject><subject>Antimicrobial activity</subject><subject>Antioxidants</subject><subject>Antioxidants - chemistry</subject><subject>Antioxidants - pharmacology</subject><subject>Ascorbic acid</subject><subject>Bacteria</subject><subject>Cancer therapies</subject><subject>Chemical compounds</subject><subject>Enzymes</subject><subject>Ethanol</subject><subject>Flavonoids</subject><subject>Flavonoids - pharmacology</subject><subject>Formulations</subject><subject>Free radicals</subject><subject>Health aspects</subject><subject>Herbal medicine</subject><subject>Hydrogen Peroxide</subject><subject>Infections</subject><subject>Materia medica, Vegetable</subject><subject>Medicinal 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Effect of Conventional Medicinal Herbs against Different Pharmacological Activity</title><author>Ali, Huma ; Ali, Daoud ; Almutairi, Bader O. ; Kumar, Gokhlesh ; Karga, Gizachew Assefa ; Masi, Chandran ; Sundramurthy, Venkatesa Prabhu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c476t-4f3a42f86484b9d9199eb3735d123783c36946de1c5f1d0a67d8fe95b96a916c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Aliphatic compounds</topic><topic>Anesthesia</topic><topic>Anti-infective agents</topic><topic>Anti-Infective Agents - pharmacology</topic><topic>Antiinfectives and antibacterials</topic><topic>Antimicrobial activity</topic><topic>Antioxidants</topic><topic>Antioxidants - chemistry</topic><topic>Antioxidants - pharmacology</topic><topic>Ascorbic acid</topic><topic>Bacteria</topic><topic>Cancer therapies</topic><topic>Chemical 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Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ali, Huma</au><au>Ali, Daoud</au><au>Almutairi, Bader O.</au><au>Kumar, Gokhlesh</au><au>Karga, Gizachew Assefa</au><au>Masi, Chandran</au><au>Sundramurthy, Venkatesa Prabhu</au><au>Ahmad, Hafiz Ishfaq</au><au>Hafiz Ishfaq Ahmad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synergistic Effect of Conventional Medicinal Herbs against Different Pharmacological Activity</atitle><jtitle>BioMed research international</jtitle><addtitle>Biomed Res Int</addtitle><date>2022-06-29</date><risdate>2022</risdate><volume>2022</volume><spage>7337261</spage><epage>7</epage><pages>7337261-7</pages><issn>2314-6133</issn><eissn>2314-6141</eissn><abstract>Triticum aestivum (Family: Poaceae), Ocimum sanctum (Family: Lamiaceae), and Tinospora cordifolia (Family: Menispermaceae) are commonly known as wheatgrass, tulsi, and giloy, respectively, which are the plants used as medicines for the treatment of various diseases. All three medicinal plants possess phenolic compounds with other important chemical constituents such as polysaccharides, aliphatic compounds, and alkaloids. The extract of these plants has been prepared and investigated for antioxidant, total phenolic content, total flavonoid content, and antimicrobial study in order to discover potential sources for new pharmaceutical formulations. To determine the antioxidant activity, a free radical scavenging assay for 2,2-diphenyl-1-picrylhydrazyl (DPPH) and hydrogen peroxide was performed using ascorbic acid as the standard. The R2 value of the prepared extract was found to be 0.9964 and 0.990 in DPPH and hydrogen peroxide scavenging activity, respectively. The phenolic and flavonoid content was found to be 87.50 μl/ml and 58.00 μl/ml, respectively. The diffusion method was used to screen the antimicrobial activity of the prepared extract sample against various microorganisms. This extract showed better results for antioxidant and antimicrobial activity.</abstract><cop>United States</cop><pub>Hindawi</pub><pmid>35813228</pmid><doi>10.1155/2022/7337261</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-6870-4798</orcidid><orcidid>https://orcid.org/0000-0002-1479-0870</orcidid><orcidid>https://orcid.org/0000-0002-6350-771X</orcidid><orcidid>https://orcid.org/0000-0003-1101-6051</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Aliphatic compounds Anesthesia Anti-infective agents Anti-Infective Agents - pharmacology Antiinfectives and antibacterials Antimicrobial activity Antioxidants Antioxidants - chemistry Antioxidants - pharmacology Ascorbic acid Bacteria Cancer therapies Chemical compounds Enzymes Ethanol Flavonoids Flavonoids - pharmacology Formulations Free radicals Health aspects Herbal medicine Hydrogen Peroxide Infections Materia medica, Vegetable Medicinal herbs Medicinal plants Medicine Metabolism Metabolites Microorganisms Ocimum sanctum Pathogens Phenolic compounds Phenols Phenols - pharmacology Plant extracts Plant Extracts - chemistry Plant Extracts - pharmacology Plants, Medicinal - chemistry Polysaccharides Saccharides Scavenging Synergistic effect Testing Tinospora cordifolia Triticum aestivum Viral infections Wheat |
| title | Synergistic Effect of Conventional Medicinal Herbs against Different Pharmacological Activity |
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