PTPα promotes fibroproliferative responses after acute lung injury

The acute respiratory distress syndrome (ARDS) is a major healthcare problem, accounting for significant mortality and long-term disability. Approximately 25% of patients with ARDS will develop an overexuberant fibrotic response, termed fibroproliferative ARDS (FP-ARDS) that portends a poor prognosi...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2022-07, Vol.323 (1), p.L69-L83
Hauptverfasser:	Aschner, Yael, Correll, Kelly A, Beke, Keriann M, Foster, Daniel G, Roybal, Helen M, Nelson, Meghan R, Meador, Carly L, Strand, Matthew, Anderson, Kelsey C, Moore, Camille M, Reynolds, Paul R, Kopf, Katrina W, Burnham, Ellen L, Downey, Gregory P
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Lung Injury - metabolism Acute Lung Injury - pathology Animals Lung - metabolism Mice Phosphoric Monoester Hydrolases - metabolism Pulmonary Fibrosis - pathology Receptor-Like Protein Tyrosine Phosphatases, Class 4 - metabolism Respiratory Distress Syndrome - metabolism Respiratory Distress Syndrome - pathology Transforming Growth Factor beta - metabolism
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