Histone variants: The unsung guardians of the genome

Histones H2A, H2B, H3, H4 and H1 are highly conserved, positively charged proteins which form a disc-shaped protein core around which genomic DNA is wrapped to form a nucleosome. Immediately following DNA synthesis, replication-dependent canonical histones help package the DNA into nucleosomes to fo...

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Veröffentlicht in:	DNA repair 2022-04, Vol.112, p.103301-103301, Article 103301
Hauptverfasser:	Phillips, Ernest O.N., Gunjan, Akash
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer Chromatin Chromatin - genetics DNA - genetics DNA damage DNA Repair Genome stability Histone variant Histones - metabolism Mammals - genetics Nucleosomes
Online-Zugang:	Volltext
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