Resolution of Visual Field Defect in Macroprolactinoma After Treatment With Cabergoline

We report the case of a 49-year-old woman presenting with amenorrhea and progressive visual field defect for one month. Endocrinological workup revealed a high concentration of serum prolactin, and magnetic resonance imaging (MRI) showed pituitary macroadenoma with extrasellar extension as well as c...

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Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2022-05, Vol.14 (5)
Hauptverfasser: Shibue, Kimitaka, Yamakawa, Momoko, Nishida, Namiko, Hamasaki, Akihiro
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Yamakawa, Momoko
Nishida, Namiko
Hamasaki, Akihiro
description We report the case of a 49-year-old woman presenting with amenorrhea and progressive visual field defect for one month. Endocrinological workup revealed a high concentration of serum prolactin, and magnetic resonance imaging (MRI) showed pituitary macroadenoma with extrasellar extension as well as compression of optic nerves. Treatment with a dopamine agonist, cabergoline, for eight weeks led to the resolution of the visual field defect accompanied by a rapid decrease in the serum prolactin level. Follow-up MRI three months after the initial diagnosis revealed alleviation of visible mechanical compression of the optic chiasm by the tumor. We considered that the absence of retinal nerve damage and prompt initiation of cabergoline contributed to the rapid recovery of the visual acuity.
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subjects Amenorrhea
Case reports
Defects
Dopamine
Endocrinology/Diabetes/Metabolism
Magnetic resonance imaging
Medical prognosis
Medical research
Neurosurgery
Ophthalmology
Optics
Patients
Pituitary gland
Research centers
Tumors
title Resolution of Visual Field Defect in Macroprolactinoma After Treatment With Cabergoline
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