Resolution of Visual Field Defect in Macroprolactinoma After Treatment With Cabergoline
We report the case of a 49-year-old woman presenting with amenorrhea and progressive visual field defect for one month. Endocrinological workup revealed a high concentration of serum prolactin, and magnetic resonance imaging (MRI) showed pituitary macroadenoma with extrasellar extension as well as c...
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Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2022-05, Vol.14 (5) |
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creator | Shibue, Kimitaka Yamakawa, Momoko Nishida, Namiko Hamasaki, Akihiro |
description | We report the case of a 49-year-old woman presenting with amenorrhea and progressive visual field defect for one month. Endocrinological workup revealed a high concentration of serum prolactin, and magnetic resonance imaging (MRI) showed pituitary macroadenoma with extrasellar extension as well as compression of optic nerves. Treatment with a dopamine agonist, cabergoline, for eight weeks led to the resolution of the visual field defect accompanied by a rapid decrease in the serum prolactin level. Follow-up MRI three months after the initial diagnosis revealed alleviation of visible mechanical compression of the optic chiasm by the tumor. We considered that the absence of retinal nerve damage and prompt initiation of cabergoline contributed to the rapid recovery of the visual acuity. |
doi_str_mv | 10.7759/cureus.25548 |
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Endocrinological workup revealed a high concentration of serum prolactin, and magnetic resonance imaging (MRI) showed pituitary macroadenoma with extrasellar extension as well as compression of optic nerves. Treatment with a dopamine agonist, cabergoline, for eight weeks led to the resolution of the visual field defect accompanied by a rapid decrease in the serum prolactin level. Follow-up MRI three months after the initial diagnosis revealed alleviation of visible mechanical compression of the optic chiasm by the tumor. We considered that the absence of retinal nerve damage and prompt initiation of cabergoline contributed to the rapid recovery of the visual acuity.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.25548</identifier><identifier>PMID: 35783884</identifier><language>eng</language><publisher>Palo Alto: Cureus Inc</publisher><subject>Amenorrhea ; Case reports ; Defects ; Dopamine ; Endocrinology/Diabetes/Metabolism ; Magnetic resonance imaging ; Medical prognosis ; Medical research ; Neurosurgery ; Ophthalmology ; Optics ; Patients ; Pituitary gland ; Research centers ; Tumors</subject><ispartof>Curēus (Palo Alto, CA), 2022-05, Vol.14 (5)</ispartof><rights>Copyright © 2022, Shibue et al. This work is published under https://creativecommons.org/licenses/by/3.0/ (the “License”). 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We considered that the absence of retinal nerve damage and prompt initiation of cabergoline contributed to the rapid recovery of the visual acuity.</description><subject>Amenorrhea</subject><subject>Case reports</subject><subject>Defects</subject><subject>Dopamine</subject><subject>Endocrinology/Diabetes/Metabolism</subject><subject>Magnetic resonance imaging</subject><subject>Medical prognosis</subject><subject>Medical research</subject><subject>Neurosurgery</subject><subject>Ophthalmology</subject><subject>Optics</subject><subject>Patients</subject><subject>Pituitary gland</subject><subject>Research centers</subject><subject>Tumors</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNpVkU9LAzEQxYMoVmpvfoCAV1uT_ZNkL0KpVoWKINUeQ5KdbVN2NzXJCn57V1tETzMwP9483kPogpIJ53lxbToPXZgkeZ6JI3SWUCbGgors-M8-QKMQtoQQSnhCODlFgzTnIhUiO0OrFwiu7qJ1LXYVfrOhUzWeW6hLfAsVmIhti5-U8W7nXa1MtK1rFJ5WETxeelCxgTbilY0bPFMa_NrVtoVzdFKpOsDoMIfodX63nD2MF8_3j7PpYmySLI3jlJpEM5brPNegMgUV04YbVpYFmFSXPdX7LhgVRBNDeKbSghKhGVc5lBWkQ3Sz1911uoHS9F68quXO20b5T-mUlf8vrd3ItfuQRZIxTkgvcHkQ8O69gxDl1nW-7T3LhBWMF5QXrKeu9lSfQwgeqt8PlMjvJuS-CfnTRPoFARR9kw</recordid><startdate>20220531</startdate><enddate>20220531</enddate><creator>Shibue, Kimitaka</creator><creator>Yamakawa, Momoko</creator><creator>Nishida, Namiko</creator><creator>Hamasaki, Akihiro</creator><general>Cureus Inc</general><general>Cureus</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20220531</creationdate><title>Resolution of Visual Field Defect in Macroprolactinoma After Treatment With Cabergoline</title><author>Shibue, Kimitaka ; 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subjects | Amenorrhea Case reports Defects Dopamine Endocrinology/Diabetes/Metabolism Magnetic resonance imaging Medical prognosis Medical research Neurosurgery Ophthalmology Optics Patients Pituitary gland Research centers Tumors |
title | Resolution of Visual Field Defect in Macroprolactinoma After Treatment With Cabergoline |
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