Biological features of canine cancer-associated fibroblasts and their influence on cancer cell invasion

Cancer-associated fibroblasts (CAFs) play an essential role in tumor invasion and metastasis. In dogs, the biological features of CAFs have not been well characterized. The purpose of this study was to investigate differences in the biological activities of canine CAFs and normal fibroblasts (NFs),...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2022, Vol.84(6), pp.784-791
Hauptverfasser:	KUDO, Ayano, YOSHIMOTO, Sho, YOSHIDA, Hiromitsu, IZUMI, Yusuke, TAKAGI, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Boyden chamber Cancer cancer-associated fibroblast Cancer-Associated Fibroblasts canine tumor Cell culture Cell Line, Tumor Cell migration Cell Movement Cell Proliferation Collagen Dog Diseases - pathology Dogs Fibroblasts Fibroblasts - metabolism Gels Infiltration invasion assay Invasiveness Metastases Neoplasm Invasiveness - pathology Surgery tumor microenvironment Tumors Wound healing
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