Palliative long-term abdominal drains for the management of refractory ascites due to cirrhosis: a consensus document
Palliative care remains suboptimal in advanced cirrhosis, in part relating to a lack of evidence-based interventions. Ascites remains the most common cirrhosis complication resulting in hospitalisation. Many patients with refractory ascites are not candidates for liver transplantation or transjugula...
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creator | Macken, Lucia Corrigan, Margaret Prentice, Wendy Finlay, Fiona McDonagh, Joanne Rajoriya, Neil Salmon, Claire Donnelly, Mhairi Evans, Catherine Ganai, Bhaskar Bedlington, Joan Steer, Shani Wright, Mark Hudson, Ben Verma, Sumita |
description | Palliative care remains suboptimal in advanced cirrhosis, in part relating to a lack of evidence-based interventions. Ascites remains the most common cirrhosis complication resulting in hospitalisation. Many patients with refractory ascites are not candidates for liver transplantation or transjugular intrahepatic portosystemic shunt, and therefore, require recurrent palliative large volume paracentesis in hospital. We review the available evidence on use of palliative long-term abdominal drains in cirrhosis. Pending results of a national trial (REDUCe 2) and consistent with recently published national and American guidance, long-term abdominal drains cannot be regarded as standard of care in advanced cirrhosis. They should instead be considered only on a case-by-case basis, pending definitive evidence. This manuscript provides consensus to help standardise use of long-term abdominal drains in cirrhosis including patient selection and community management. Our ultimate aim remains to improve palliative care for this under researched and vulnerable cohort. |
doi_str_mv | 10.1136/flgastro-2022-102128 |
format | Article |
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Ascites remains the most common cirrhosis complication resulting in hospitalisation. Many patients with refractory ascites are not candidates for liver transplantation or transjugular intrahepatic portosystemic shunt, and therefore, require recurrent palliative large volume paracentesis in hospital. We review the available evidence on use of palliative long-term abdominal drains in cirrhosis. Pending results of a national trial (REDUCe 2) and consistent with recently published national and American guidance, long-term abdominal drains cannot be regarded as standard of care in advanced cirrhosis. They should instead be considered only on a case-by-case basis, pending definitive evidence. This manuscript provides consensus to help standardise use of long-term abdominal drains in cirrhosis including patient selection and community management. Our ultimate aim remains to improve palliative care for this under researched and vulnerable cohort.</description><identifier>ISSN: 2041-4137</identifier><identifier>EISSN: 2041-4145</identifier><identifier>DOI: 10.1136/flgastro-2022-102128</identifier><identifier>PMID: 35812034</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Abdomen ; Alcohol ; Antibiotics ; ASCITES ; Caregivers ; CLINICAL TRIALS ; Community health care ; Contraindications ; COVID-19 ; Feasibility studies ; Gastroenterology ; Hospitalization ; Hospitals ; Liver ; LIVER CIRRHOSIS ; Liver diseases ; Mortality ; Palliative care ; Patients ; PERITONITIS ; Systematic review ; Transplants & implants</subject><ispartof>Frontline gastroenterology, 2022-08, Vol.13 (e1), p.e116-e125</ispartof><rights>Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2022 Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>Author(s) (or their employer(s)) 2022. No commercial re-use. See rights and permissions. Published by BMJ. 2022</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b505t-9b5196a7f3a508f6575b8932d25a4cafac98e4d44a51cd5b3d334ae0b88f67ec3</citedby><cites>FETCH-LOGICAL-b505t-9b5196a7f3a508f6575b8932d25a4cafac98e4d44a51cd5b3d334ae0b88f67ec3</cites><orcidid>0000-0001-7655-7284 ; 0000-0001-7046-241X ; 0000-0001-7021-8409 ; 0000-0001-8549-9231 ; 0000-0003-3892-2206</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234735/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234735/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,313,314,727,780,784,792,885,27921,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/35812034$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Macken, Lucia</creatorcontrib><creatorcontrib>Corrigan, Margaret</creatorcontrib><creatorcontrib>Prentice, Wendy</creatorcontrib><creatorcontrib>Finlay, Fiona</creatorcontrib><creatorcontrib>McDonagh, Joanne</creatorcontrib><creatorcontrib>Rajoriya, Neil</creatorcontrib><creatorcontrib>Salmon, Claire</creatorcontrib><creatorcontrib>Donnelly, Mhairi</creatorcontrib><creatorcontrib>Evans, Catherine</creatorcontrib><creatorcontrib>Ganai, Bhaskar</creatorcontrib><creatorcontrib>Bedlington, Joan</creatorcontrib><creatorcontrib>Steer, Shani</creatorcontrib><creatorcontrib>Wright, Mark</creatorcontrib><creatorcontrib>Hudson, Ben</creatorcontrib><creatorcontrib>Verma, Sumita</creatorcontrib><creatorcontrib>British Association for the Study of the Liver/British Society of Gastroenterology (BASL/BSG) End of Life Special Interest Group</creatorcontrib><title>Palliative long-term abdominal drains for the management of refractory ascites due to cirrhosis: a consensus document</title><title>Frontline gastroenterology</title><addtitle>Frontline Gastroenterol</addtitle><addtitle>Frontline Gastroenterol</addtitle><description>Palliative care remains suboptimal in advanced cirrhosis, in part relating to a lack of evidence-based interventions. Ascites remains the most common cirrhosis complication resulting in hospitalisation. Many patients with refractory ascites are not candidates for liver transplantation or transjugular intrahepatic portosystemic shunt, and therefore, require recurrent palliative large volume paracentesis in hospital. We review the available evidence on use of palliative long-term abdominal drains in cirrhosis. Pending results of a national trial (REDUCe 2) and consistent with recently published national and American guidance, long-term abdominal drains cannot be regarded as standard of care in advanced cirrhosis. They should instead be considered only on a case-by-case basis, pending definitive evidence. This manuscript provides consensus to help standardise use of long-term abdominal drains in cirrhosis including patient selection and community management. 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Ascites remains the most common cirrhosis complication resulting in hospitalisation. Many patients with refractory ascites are not candidates for liver transplantation or transjugular intrahepatic portosystemic shunt, and therefore, require recurrent palliative large volume paracentesis in hospital. We review the available evidence on use of palliative long-term abdominal drains in cirrhosis. Pending results of a national trial (REDUCe 2) and consistent with recently published national and American guidance, long-term abdominal drains cannot be regarded as standard of care in advanced cirrhosis. They should instead be considered only on a case-by-case basis, pending definitive evidence. This manuscript provides consensus to help standardise use of long-term abdominal drains in cirrhosis including patient selection and community management. 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subjects | Abdomen Alcohol Antibiotics ASCITES Caregivers CLINICAL TRIALS Community health care Contraindications COVID-19 Feasibility studies Gastroenterology Hospitalization Hospitals Liver LIVER CIRRHOSIS Liver diseases Mortality Palliative care Patients PERITONITIS Systematic review Transplants & implants |
title | Palliative long-term abdominal drains for the management of refractory ascites due to cirrhosis: a consensus document |
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