In vitro eradication of abasic site-mediated DNA–peptide/protein cross-links by Escherichia coli long-patch base excision repair

Apurinic/apyrimidinic (AP or abasic) sites are among the most abundant DNA lesions. Numerous proteins within different organisms ranging from bacteria to human have been demonstrated to react with AP sites to form covalent Schiff base DNA–protein cross-links (DPCs). These DPCs are unstable due to th...

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Veröffentlicht in:	The Journal of biological chemistry 2022-07, Vol.298 (7), p.102055-102055, Article 102055
Hauptverfasser:	Bryan, Cameron, Wei, Xiaoying, Wang, Zhishuo, Yang, Kun
Format:	Artikel
Sprache:	eng
Schlagworte:	abasic site base excision repair DNA damage DNA polymerase I DNA repair DNA–protein cross-link endonuclease IV
Online-Zugang:	Volltext
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