Subcutaneous Administration of a Nitric Oxide-Releasing Nanomatrix Gel Ameliorates Obesity and Insulin Resistance in High-Fat Diet-Induced Obese Mice

Nitric oxide (NO) is a gaseous signaling molecule, which plays crucial roles in various biological processes, including inflammatory responses, metabolism, cardiovascular functions, and cognitive function. NO bioavailability is reduced with aging and cardiometabolic disorders in humans and rodents....

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Veröffentlicht in:	ACS applied materials & interfaces 2022-05, Vol.14 (17), p.19104-19115
Hauptverfasser:	Ren, Guang, Hwang, Patrick Tae Joon, Millican, Reid, Shin, Juhee, Brott, Brigitta C, van Groen, Thomas, Powell, Craig M, Bhatnagar, Sushant, Young, Martin E, Jun, Ho-Wook, Kim, Jeong-a
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue, Brown - metabolism Animals Biological and Medical Applications of Materials and Interfaces Diet, High-Fat - adverse effects Insulin Insulin Resistance - physiology Male Mice Mice, Inbred C57BL Mice, Obese Nitric Oxide - metabolism Obesity - drug therapy Obesity - metabolism
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